Costs of Treating Uncomplicated Sickle Cell Complications in a Day Hospital Setting in Equatorial Africa. [PDF]
Sickle cell disease (SCD) is a major public health concern in Africa. SCD healthcare expenses are covered by personal finances in the Congo due to the absence of universal public health insurance. Various strategies have been implemented to minimize this economic burden, including an outpatient management strategy. The present study evaluated the costs
Ngolet LO +7 more
europepmc +2 more sources
Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification. [PDF]
ABSTRACT Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...
El Aouhel S +10 more
europepmc +2 more sources
Mitochondrial retention in mature red blood cells from patients with sickle cell disease is associated with stress erythropoiesis but not with proinflammatory state. [PDF]
HemaSphere, Volume 8, Issue 11, November 2024.
Romana M +14 more
europepmc +2 more sources
PI-09: LESSONS LEARNED FROM ONE DECADE EXPERIENCE OF THE « CENTRE DE RECHERCHE ET DE LUTTE CONTRE LA DRÉPANOCYTOSE (CRLD) » IN BAMAKO, MALI. [PDF]
HemaSphere, Volume 6, Issue S4, Page 13-14, August 2022.
D. D, A. G.
europepmc +2 more sources
Is chest X-ray still relevant for acute chest syndrome diagnosis? [PDF]
Health Science Reports, Volume 7, Issue 5, May 2024.
Pelinski Y +7 more
europepmc +2 more sources
A case‐control study nested in the CADRE multinational African cohort was conducted in Bamako and Dakar in 235 patients with sickle cell anemia (SCA) to test multiple biological and functional markers as potential markers of six different SCA‐related chronic organ damage.
Brigitte Ranque +16 more
wiley +1 more source
P-025: ABNORMAL MITOCHONDRIA RETENTION IN MATURE RED BLOOD CELLS OCCURS NOT ONLY IN SS BUT ALSO SC PATIENTS AND IS ASSOCIATED WITH HEMOLYTIC MARKERS [PDF]
HemaSphere, Volume 6, Issue S4, Page 29-29, August 2022.
M. R +10 more
europepmc +2 more sources
Summary Data on acute chest syndrome (ACS) in adult sickle cell disease patients are scarce. In this study, we describe 105 consecutive ACS episodes in 81 adult patients during a 32‐month period and compare the characteristics as a function of the time to onset after hospital admission for a vaso‐occlusive crisis (VOC), that is early‐onset episodes ...
Geoffrey Cheminet +8 more
wiley +1 more source
Summary Hypoxia‐mediated red blood cell (RBC) sickling is central to the pathophysiology of sickle cell disease (SCD). The signalling nucleoside adenosine is thought to play a significant role in this process. This study investigated expression of the erythrocyte type 1 equilibrative nucleoside transporter (ENT1), a key regulator of plasma adenosine ...
Bérengère Koehl +13 more
wiley +1 more source
O-06: E-SICKLE CELL DISEASE: A FRENCH SPEAKING TRAINING PLATFORM TARGETING ALL LEVELS OF THE HEALTHCARE SYSTEM [PDF]
HemaSphere, Volume 6, Issue S4, Page 4-5, August 2022.
M. C, C. P, V. T, I. D, J. E.
europepmc +2 more sources

