Results 11 to 20 of about 2,155 (150)

Sickle cell anemia and pregnancy: Profile of hemodynamic changes in sickle cell pregnant women in Kinshasa

eJHaem, 2023
Pregnancy is accompanied by hormonal changes. These relate mainly to progesterone and placenate growth factor. Hemodynamic changes are also observed. in a sickle cell pregnant woman, all these changes have a direct effect on hypoxia.
Tite Minga Mikobi, Nelly Ciombo Kamuanya, Emmanuelle Ketsia Bokashanga Mikobi, Thérèse Ilunga Kalela, Pierre Zalagile Akilimali, Prosper Tshilobo Lukusa   +5 more
doaj   +2 more sources

Polygenic scores in the diagnosis of abnormal complete blood count values. [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 6, June 2026.
Srour M, Lecluze E, Chacowry E, Saby M, Pincez T.   +4 more
europepmc   +2 more sources

Costs of Treating Uncomplicated Sickle Cell Complications in a Day Hospital Setting in Equatorial Africa. [PDF]

Anemia
Sickle cell disease (SCD) is a major public health concern in Africa. SCD healthcare expenses are covered by personal finances in the Congo due to the absence of universal public health insurance. Various strategies have been implemented to minimize this economic burden, including an outpatient management strategy. The present study evaluated the costs
Ngolet LO, Taylor J, de Chabervy Atipo A, Mikia CP, Bango C, Bantsimba FS, Ondzotto Ibatta I, Dokekias AE.   +7 more
europepmc   +2 more sources

Mitochondrial retention in mature red blood cells from patients with sickle cell disease is associated with stress erythropoiesis but not with proinflammatory state. [PDF]

Hemasphere
HemaSphere, Volume 8, Issue 11, November 2024.
Romana M, Laurance S, Hardy-Dessources MD, Claer L, Ravion S, Dorgham K, Garnier Y, Kuznicki L, Tarer V, Tressières B, Lefevre SD, Baccini V, Ostuni MA, Le Van Kim C, Etienne-Julan M.   +14 more
europepmc   +2 more sources

Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification. [PDF]

Am J Hematol
ABSTRACT Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...
El Aouhel S, Bellegarde V, Da Silva Faria S, St-Laurent T, Lecluze E, Pham Hung d'Alexandry d'Orengiani AL, Galactéros F, Bartolucci P, Legault MA, Lettre G, Pincez T.   +10 more
europepmc   +2 more sources

Neonatal Screening for Sickle Cell Disease in Congo

Anemia, 2022
Introduction. Sickle cell disease is an autosomal recessive inherited disorder due to the mutation of a gene coding for the globin beta chain. The aim of this study is to update the epidemiological data on hemoglobinoses, in particular sickle cell ...
Alexis Elira Dokekias, Lethso Thibaut Ocko Gokaba, Josué Simo Louokdom, Lydie Ngolet Ocini, Firmine Olivia Galiba Atipo Tsiba, Coreillia Irène Ondzotto Ibatta, Quentin Ngoma Kouandzi, Serge Talomg Tamekue, Jayne Chelsea Bango, Jade Vanessa Nziengui Mboumba, Simon Charles Kobawila   +10 more
doaj   +1 more source

Dengue in hospitalized children with sickle cell disease: A retrospective cohort study in the French departments of America

Journal of Infection and Public Health, 2020
Background: To describe the characteristics of dengue in sickle cell children and try to identify risk factors of severity. Methods: In this retrospective study, we describe the evolution according to genotype (SS or SC and controls) and severity ...
Narcisse Elenga, Donald Celicourt, Blandine Muanza, Gisèle Elana, Sévérine Hocquelet, Vanessa Tarer, Frédéric Maillard, Gérard Sibille, Lydia Divialle Doumdo, Marie Petras, Benoit Tressières, Maryse Etienne-Julan   +11 more
doaj   +1 more source

Is chest X-ray still relevant for acute chest syndrome diagnosis? [PDF]

Health Sci Rep
Health Science Reports, Volume 7, Issue 5, May 2024.
Pelinski Y, Guindo A, Kassasseya C, Diallo D, Arlet JB, Mekontso Dessap A, Habibi A, Bartolucci P.   +7 more
europepmc   +2 more sources

Evaluation in silico de l’activité anti-drépanocytaire de quelques composés de l’huile essentielle de Lippia multiflora Moldenke (Verbenaceae)

Revue Congolaise des Sciences et Technologies, 2023
Dans le contexte de la drépanocytose, une maladie génétique affectant les globules rouges, la recherche de traitements alternatifs est cruciale. L'objectif de cette étude est d'utiliser des simulations informatiques pour prédire l'efficacité de certains ...
C.A. Masengo, K.N. Ngbolua, S.O. Mihigo, G.B. Ilumbe, D.D. Tshilanda, D.S.T. Tshibangu, V. Mudogo, P.T Mpiana   +7 more
doaj   +1 more source

Symposium - De la recherche à la production industrielle des produits de santé (Présentations d'expériences réussies) - Expérience n°3 : Processus de Recherche-Développement (R&D) et production d’un phytomédicament destiné au traitement de la drépanocytose : FACA

Journal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Dr Salfo OUEDRAOGO, PharmD, M.Sc. Pharma, PhD, Maître de Recherche en Pharmacie Galénique et Industrielle, Chef de service Production CNRST/IRSS/MEPHATRA/PH, Pharmacien chef de l’Unité de Production Pharmaceutique (U-PHARMA), Tel : (+226) 70 45 89 36/78
Salfo OUEDRAOGO
doaj   +1 more source