Results 41 to 50 of about 1,539,229 (306)
CFD Analysis of The Hydraulic Turbine Draft Tube to Improve System Efficiency
MATEC Web of Conferences, 2016 Demand of the power is increasing day by day with the development of the science and technology. Development of the renewable energy sector has become essential issue at the present situation due to the limited source of the non-renewable energy.
Chakrabarty Spandan +2 more
doaj +1 more source
Study of Flow Characteristics inside Francis Turbine Draft Tube with Adjustable Guide Vanes
, 2021 Numerical investigation was performed on a semi-model (one stay vane, two guide vanes, one runner passage inclusive of one main and one splitter blade, and the draft tube) of a high-head Francis turbine model with adjustable guide vanes in the draft tube.
J. Joy, M. Raisee, M. Cervantes
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Manipulation of the swirling flow instability in hydraulic turbine diffuser by different methods of water injection [PDF]
EPJ Web of Conferences, 2018 Vortex rope, which induces substantial pressure pulsations, arises in the draft tube (diffuser) of Francis turbine for off-design operating conditions.
Rudolf Pavel +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Werle´–Legendre Separation in a Hydraulic Machine Draft Tube [PDF]
Journal of Fluids Engineering, 2002 The three-dimensional turbulent flow in a compact hydraulic machine elbow draft tube is numerically investigated for several operating conditions, covering an extended range around the best efficiency point. Comparisons with the experimental data are presented as validation.
Mauri, Sebastiano +2 more
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source