Results 51 to 60 of about 304,926 (297)

Effect of Runner Solidity on Performance of Elbow Draft Tube

, 2012
The significant amount of kinetic energy comes out of runner in reaction turbines and the draft tube is used to recover this kinetic energy into useful pressure energy.
Kharea, Ruchi, Mittalc, Sushil Kumar, Prasadb, Vishnu   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Drying of biological materials in a spout-fluid bed with a draft tube [PDF]

Hemijska Industrija, 2002
The possibility of applying a spout-fluid bed with a draft tube and conical bottom was investigated for drying fluid media with a certain content of suspended material was investigated.
Povrenović Dragan S., Dimitrijević-Branković Suzana I.   +1 more
doaj   +1 more source

Study of the effects of modified draft tube with inclined conical diffuser on draft tube and upstream region

Journal of Physics: Conference Series
Abstract Various countermeasures including geometry optimization have been proposed and proved to have a huge impact on flow filed within the draft tube in order to mitigate the vortex rope and the induced pressure fluctuations for Francis turbine under part load operation. However, the effect of these approaches on the hydro-dynamics in
Xing Zhou, Quanshui Huang, Xinyi Hu, Xiangyu Dai   +3 more
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Experimental studies into the thermal-hydraulic performance of the VK-300 reactor based on a draft tube model

Nuclear Energy and Technology, 2015
The paper presents an experimental study into the thermal-hydraulic performance of the VK-300 reactor based on a model of a single draft tube at a pressure of 3.4MPa, various flow rates and the model inlet relative enthalpies of –0.05 to 0.2.
N.P. Serdun, V.I. Ignatenko, G.S. Kotikov   +2 more
doaj   +1 more source

DESIGN OPTIMISATION OF CONICAL DRAFT TUBE OF HYDRAULIC TURBINE

, 2020
The optimum performance of draft tube is an important aspect in the design of hydraulic turbine, which can be achieved by varying the shape and size of draft tube.
Dr Ruchi Khare, Dr Vishnu Prasad, Mitrasen Verma   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source