Results 51 to 60 of about 1,539,229 (306)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Drying of biological materials in a spout-fluid bed with a draft tube [PDF]

Hemijska Industrija, 2002
The possibility of applying a spout-fluid bed with a draft tube and conical bottom was investigated for drying fluid media with a certain content of suspended material was investigated.
Povrenović Dragan S., Dimitrijević-Branković Suzana I.   +1 more
doaj   +1 more source

Reduced order model of draft tube flow

IOP Conference Series: Earth and Environmental Science, 2014
Swirling flow with compact coherent structures is very good candidate for proper orthogonal decomposition (POD), i.e. for decomposition into eigenmodes, which are the cornerstones of the flow field. Present paper focuses on POD of steady flows, which correspond to different operating points of Francis turbine draft tube flow. Set of eigenmodes is built
P Rudolf, D Štefan
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Inner Flow Analysis of Kaplan Turbine under Off-Cam Conditions

Energies
Kaplan turbines are widely utilized in low-head and large flow power stations. This paper employs Computational Fluid Dynamics (CFD) to complete numerical calculations of the full flow channel under different blade angles and various guide vane openings,
Dandan Yan, Haiqiang Luo, Weiqiang Zhao, Yibin Wu, Lingjiu Zhou, Xiaofu Fan, Zhengwei Wang   +6 more
doaj   +1 more source

Optimization of a Draft Tube using Statistical Techniques- DOE and 2D Computational Fluid Dynamic Analysis

Journal of Applied Fluid Mechanics, 2021
The draft tube is one of the main components that integrate a turbine, since it has the function of recovering the residual kinetic energy after the runner by the pressure energy.
A. C. Barkett Botan, R. G. Ramirez Gustavo, G. L. Tiago Filho, E. R. da Silva   +3 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experimental investigation of draft tube flow instability

IOP Conference Series: Earth and Environmental Science, 2010
The draft tube of a hydraulic turbine is the component where the flow exiting the runner is decelerated, thereby converting the excess of kinetic energy into static pressure. However, in some refurbishment cases, the installation of an upgraded runner with an old draft- tube leads to an undesirable efficiency drop as the discharge is increased above ...
S Tridon, S Barre, G D Ciocan, P Leroy, C Ségoufin   +4 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source