Results 61 to 70 of about 1,849,126 (285)

The effects of an enriched environment and teacher intervention on the dramatic and sociodramatic play of children [PDF]

open access: yes, 2007
This study examined the effects of an enriched environment and teacher intervention on the dramatic and sociodramatic play of four to five year old children in Singapore.
Lu Soo Ai, Theresa
core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Le ‘maestre’ di Adelaide Ristori: tracce di una trasmissione generazionale del mestiere

open access: yesDrammaturgia, 2023
This paper proposes a comparison between Adelaide Ristori and the actresses of the previous generation searching for traces of an unwritten transmission of the theatrical craft.
Giulia Bravi
doaj  

The proportional representation review.

open access: yes, 1893
Continued as a department of: Direct legislation record and the proportional representation review."A quarterly magazine, devoted to the reformation of the method of electing representatives."Title from cover.Mode of access: Internet.Revived and absorbed
American Proportional Representation League.
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Various aspects of realization of the plot “liberation from the oppressors” in russian fairytale drama of 1920-1940’s (on the example of the plays “Dragon” by E.L. Shvarts, “Three Fat Men” by Yu.K. Olesha and “The Town of Masters, or The Tale about Two Humpbacks” by T.G. Gabbe)

open access: yesRUDN Journal of Studies in Literature and Journalism, 2014
In this paper on the example of three plays written in 1920-40s., the features of realization of the motive of “liberation from the oppressors” widely used in Russian Soviet literature for children is discussed.
A I Safuanova
doaj  

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