Results 81 to 90 of about 1,849,126 (285)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Il fondo Adelaide Ristori al Museo Biblioteca dell’Attore di Genova

open access: yesDrammaturgia
The Adelaide Ristori Archive has been kept at the Museo Biblioteca dell’Attore in Genoa since 1967, after the donation of Irma Castren Capranica del Grillo.
Donatella Mezzani
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Whitehaven Dramatic Club presents "A White Mountain Boy"

open access: yes, 1904
"A White Mountain Boy" at White Haven, Tenn. July 21, 1904, benefit of White Haven Dramatic Club. There are advertisements for Hare & Beasleys, J. W. Hale & Son, A. G. Wagner & Co.
White Haven Dramatic Club
core  

Parliamentary Representation: A Cross-national Study of Candidates’ Views [PDF]

open access: yes, 2019
This study explores political elites’ self-conceptualisation of parliamentary representation by using data on nearly 7,000 candidates encompassing eighteen elections in fifteen countries.
Sudulich, Laura   +2 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The psycholinguistic representation of lexical tones: the effect of phonetic context on tone processing in Cantonese-speaking children

open access: yes, 2011
No abstract ...
Tong, X   +5 more
core  

Representation of sexism in bombshell film (2019)

open access: yes, 2023
Bombshell is a 2019 American biographical drama film directed by Jay Roach and written by Charles Randolph. This research analyzes the representation of sexism in the Bombshell film (2019).
Eli yupina siregar
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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