Results 81 to 90 of about 1,849,126 (285)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Il fondo Adelaide Ristori al Museo Biblioteca dell’Attore di Genova
The Adelaide Ristori Archive has been kept at the Museo Biblioteca dell’Attore in Genoa since 1967, after the donation of Irma Castren Capranica del Grillo.
Donatella Mezzani
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Whitehaven Dramatic Club presents "A White Mountain Boy"
"A White Mountain Boy" at White Haven, Tenn. July 21, 1904, benefit of White Haven Dramatic Club. There are advertisements for Hare & Beasleys, J. W. Hale & Son, A. G. Wagner & Co.
White Haven Dramatic Club
core
Parliamentary Representation: A Cross-national Study of Candidates’ Views [PDF]
This study explores political elites’ self-conceptualisation of parliamentary representation by using data on nearly 7,000 candidates encompassing eighteen elections in fifteen countries.
Sudulich, Laura +2 more
core +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Representation of sexism in bombshell film (2019)
Bombshell is a 2019 American biographical drama film directed by Jay Roach and written by Charles Randolph. This research analyzes the representation of sexism in the Bombshell film (2019).
Eli yupina siregar
core
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source

