Results 31 to 40 of about 2,647,604 (292)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Experimental and simulation study on the deformation behavior, mechanical properties and microstructure of Ti–6Al–4V alloy wires fabricated by hot drawing

Journal of Materials Research and Technology
In this study, a combined experimental and simulation method was proposed to determine the friction coefficient involved in wire drawing processes. Subsequently, the hot drawing experiments and finite element analysis (FEA) of Ti–6Al–4V alloy wire were ...
Zhijie Gao, Yaozong Mao, Zhiqiang Zhang, Chunguang Bai, Li Zhou   +4 more
doaj   +1 more source

Numerical analysis to determine the impact of land subsidence on high-speed railway routes in Beijing, China [PDF]

Proceedings of the International Association of Hydrological Sciences, 2015
More than 10 high-speed railway routes with top speeds of 300 km h−1 are expected to be operational from Beijing by the year 2020. However, the safety of these routes is affected by the occurrence of land subsidence.
C. Ye, Y. Yang, Y. Yang, F. Tian, Y. Luo, Y. Luo, Y. Zhou, Y. Zhou   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Drawing of Hexagonal Shapes from Cylindrical Cups [PDF]

Engineering and Technology Journal, 2016
The main aim of this work is design and manufacturing cylindrical and hexagonal dies to produce hexagonal cups from transform the cylindrical cups to hexagonal cups and affect of wall corner radii of die.
Waleed Khalid Jawed, Sabih Salman Dawood
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Optimization and finite element analysis of the drawing process for rolling linear guide slider [PDF]

Journal of Hebei University of Science and Technology
Aiming to address the issue of increased production costs caused by the five-pass cold drawing forming for the sliding block in the rolling linear guide pair in a factory in Hebei Province, this study investigated the influence of parameters such as die ...
Yan GAO, Runzheng WANG, Wang LI, Haikun MA, Honggang MO, Pengbiao HAN   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Influence of interactive learning support system using augmented reality on 3D object drawing

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
The 3D pen is a tool that can output a melted resin from a pen tip to form a 3D object. In order to shape an object using a 3D pen, it is necessary to practice it and understand how to use it, and many beginners find it difficult to handle.
Masashi OKUBO, Yukari MIZUNO
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source