Results 91 to 100 of about 392,436 (266)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Territoires émergents d'Amazonie : analyse comparée des dynamiques territoriales dans le Baixo Amazonas et le Nordeste Paraense

open access: yesConfins, 2015
While the deterioration of the Amazon’s resources has drawn much attention, spatial dynamics at stake are still poorly understood. At the crossing of the Amazon of roads and Amazon of rivers classical models, new territorial dynamics are taking shape. To
Etienne Polge   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Evaluating the Balloon Analogue Risk Task (BART) as a Predictor of Risk Taking in Adolescent and Adult Male Drivers.

open access: yes, 2007
Young drivers between the ages of 15 and 24 are overrepresented in automobile crash statistics worldwide. Despite the common assumption that young drivers are more at risk of crashing than older drivers due to inexperience, age appears to be the main ...
Gordon, Mark Adam
core  

How Integrated Marketing Communications (IMC) works? A theoretical review and an analysis of its main drivers and effects

open access: yesCommunication & Society (Formerly Comunicación y Sociedad), 2012
Since the mid-1990’s, the concept of Integrated Marketing Communications (IMC) has come to the fore and attracted considerable attention in the literature.
Lucía Porcu   +2 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Age vs. Experience: Evaluation of a Video Feedback Intervention for Newly Licensed Teen Drivers, TPF-5(207), 2013

open access: yes, 2013
This project examines the effects of age, experience, and video-based feedback on the rate and type of safety-relevant events captured on video event recorders in the vehicles of three groups of newly licensed young drivers: 1.

core  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Train drivers' alcohol limit four times higher than taxi and bus drivers'.

open access: yes, 2018
Current legislation which permits train drivers and other railway workers to have four times more alcohol in their blood than other professional drivers “fell between the gaps”, an Oireachtas Committee has heard.....
Burns, Sarah
core  

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