Results 91 to 100 of about 958,985 (302)

Evaluating the Balloon Analogue Risk Task (BART) as a Predictor of Risk Taking in Adolescent and Adult Male Drivers. [PDF]

open access: yes, 2007
Young drivers between the ages of 15 and 24 are overrepresented in automobile crash statistics worldwide. Despite the common assumption that young drivers are more at risk of crashing than older drivers due to inexperience, age appears to be the main ...
Gordon, Mark Adam
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Age vs. Experience: Evaluation of a Video Feedback Intervention for Newly Licensed Teen Drivers, TPF-5(207), 2013 [PDF]

open access: yes, 2013
This project examines the effects of age, experience, and video-based feedback on the rate and type of safety-relevant events captured on video event recorders in the vehicles of three groups of newly licensed young drivers: 1.

core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Addressing Sexual Violence: The Reality and Strategies of Female Ojek (Motorbike Ride Service) Drivers in Banyumas Regency

open access: yesYinyang: Jurnal Studi Islam, Gender dan Anak
The emergence of the phenomenon of female online motorcycle taxi drivers in the Banyumas district shows that women’s emancipation has taken place. Transportation has become a daily need for Banyumas residents, this is used by some women to earn a living.
Noer Anissa Rakhmawati   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Effect of Educational Program to Decrease Substance Abuse among Suburban Bus Drivers Based on Theory of Planned Behavior

open access: yesپزشکی بالینی ابن سینا, 2015
Introduction & Objective: Driving under the influence of drugs is considered a social pathology that has adverse effects on a society. This study aimed to investigate the effect of substance abuse educational program among the bus drivers on the basis of
Babak Moeini   +4 more
doaj  

Analysing the Impact of Human Error on the Severity of Truck Accidents through HFACS and Bayesian Network Models

open access: yesSafety
Truck accidents are a prevalent global issue resulting in substantial economic losses and human lives. One of the principal contributing factors to these accidents is driver error.
Dwitya Harits Waskito   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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