Results 71 to 80 of about 392,436 (266)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Telemedicine: A Drivers Analysis
, 2007 This paper will introduce telemedicine in an historical context. We will then evaluate Pelton's five drivers of telecommunication in terms of telemedicine. Pelton's five drivers are technology, finance, standards, regulation and services.
Al Ys Is +1 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Executive Functions and Risk Propensity in Adolescent and Adult Male Drivers: A Comparison
, 2010 Young drivers between the ages of 16 and 24 are over-represented in motor-vehicle accident statistics worldwide. Several studies suggest that age could be a major crash risk factor in young drivers because their frontal lobes are not yet fully developed.
Moleni, James
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Low back pain and risk factors for low back pain in car drivers
, 2008 The cause of low back pain in populations of professional drivers is uncertain. A literature review revealed factors that seem to be associated with low back pain (e.g.
Gallais, Lenka
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2013 One of the major challenges facing novice drivers seems to be adequately scanning, detecting, and responding to hazards which present during the course of everyday driving; a process that involves ‘reading the road’ and modifying driver behaviour ...
Starkey, Nicola J. +2 more
core
oreopie/flood-compounding-drivers: v0.0.2
, 2023 This repository contains the code to reproduce the main procedure for identifying the compounding drivers of river floods and the associated flood complexity, as presented in the paper submitted to Journal.
Shijie Jiang
core +1 more source