Results 101 to 110 of about 1,957,125 (285)

Dangerous Driver [PDF]

open access: yesJournal of Clinical Sleep Medicine, 2011
Klark B, Turpen, Mary H, Wagner
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Territoires émergents d'Amazonie : analyse comparée des dynamiques territoriales dans le Baixo Amazonas et le Nordeste Paraense

open access: yesConfins, 2015
While the deterioration of the Amazon’s resources has drawn much attention, spatial dynamics at stake are still poorly understood. At the crossing of the Amazon of roads and Amazon of rivers classical models, new territorial dynamics are taking shape. To
Etienne Polge   +2 more
doaj   +1 more source

Analyzing combined vehicle routing and break scheduling from a distributed decision making perspective [PDF]

open access: yes, 2009
We analyze the problem of combined vehicle routing and break scheduling from a distributed decision making perspective. The problem of combined vehicle routing and break scheduling can be defined as the problem of finding vehicle routes to serve a set of
Kok, A.L.   +3 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

How Integrated Marketing Communications (IMC) works? A theoretical review and an analysis of its main drivers and effects

open access: yesCommunication & Society (Formerly Comunicación y Sociedad), 2012
Since the mid-1990’s, the concept of Integrated Marketing Communications (IMC) has come to the fore and attracted considerable attention in the literature.
Lucía Porcu   +2 more
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Lumbopelvic Movements Influencing the Perception of Back Pain in a Driving Static Posture, Made from a Device Placed on the Seat

open access: yesRevista Ciencias de la Salud, 2014
Introduction: Evidence shows an association between lbp and sitting posture there. Moreover, the macro repositioning effected on the seat is the natural response of the body because of the perceived inconvenience versus time prolonged, but the evidence ...
María Fernanda Maradei G.   +1 more
doaj  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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