Results 101 to 110 of about 1,796,768 (309)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Effect of using an in-vehicle smart driving aid on real-world driver performance [PDF]
, 2014 A smart driving system (providing both safety and fuel-efficient driving advice in real time in the vehicle) was evaluated in real-world on-road driving trials to see if any measurable beneficial changes in driving performance would be observed.
Fowkes, Mark +2 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Smart driving aids and their effects on driving performance and driver distraction [PDF]
, 2009 In-vehicle information systems have been shown to increase driver workload and cause distraction; both of which are causal factors for accidents. This simulator study evaluates the impact that two designs for a smart driving aid, and scenario complexity ...
Young, Mark S. +3 more
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Driving: Pre-Cognition and Driving [PDF]
, 2016 The most significant recent developments in the study of car travel have come from mobility studies rather than the long dominant field of transport psychology (Cresswell 2006; Hannam et al. 2006; Sheller and Urry 2006). In sociology John Urry (2000, 2004) has argued that we need to rethink how we conceptualise society in tandem with how we ...
openaire +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Road Service Performance Based On Integrated Road Design Consistency (IC) Along Federal Road F0023
MATEC Web of Conferences, 2017 Road accidents are one of the world’s largest public health and injury prevention problems. In Malaysia, the west coast area of Malaysia been stated as the highest motorcycle fatalities and road accidents are one of the factors that cause of death and ...
Zainal Zaffan Farhana +2 more
doaj +1 more source
Assessing the relationship between driving skill, driving stress, and driving behavior
Journal of Safety ResearchDriving skill, driving stress, and driving behavior have an effect on road traffic safety. Most previous studies have investigated the effect of driving skill or driving stress on driving behavior separately. However, the relationship and effect mechanism between driving skill, driving stress, and driving behavior have been neglected.1207 licensed ...
Yang, Liu +3 more
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source