Results 101 to 110 of about 1,723,395 (300)
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Research on energy management strategy considering battery life for plug-in hybrid electric vehicle
Advances in Mechanical Engineering, 2018 To improve the fuel efficiency and battery life-span of plug-in hybrid electric vehicle, the energy management strategy considering battery life decay is proposed. This strategy is optimized by genetic algorithm, aiming to reduce the fuel consumption and
Jianjun Hu +3 more
doaj +1 more source
Design cycles for a given driving mission
, 2018 Representative driving cycles are of key importance for design and dimensioning of powertrains. One approach for generation of representatives driving cycles is to define relevant driving missions which include different street types, obstacles and ...
Frisk, Erik, +2 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Evaluation, Generation, and Transformation of Driving Cycles
, 2015 Driving cycles are important components for evaluation and design of vehicles. They determine the focus of vehicle manufacturers, and indirectly they affect the environmental impact of vehicles since the vehicle control system is usually tuned to one or ...
Peter Nyberg +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2009 In the frame of the ARTEMIS European research project, a compilation and synthesis of previous works has been considered to derive a set of reference real-world driving cycles.
Andre, Michel
core +3 more sources
EnergiesHydrogen fuel cell buses (HFCBs) offer a promising zero-emission solution for sustainable public transportation. However, the high energy consumption of auxiliary systems, particularly heating, ventilation and air conditioning (HVAC), significantly ...
Zarina Omarova +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Proposal of a dynamic performance index to analyze driving pattern effect on car emissions [PDF]
, 2009 The contributions of driver behaviour as well as surrounding infrastructure are decisive on pollutant emissions from vehicles in real traffic situations.
Casanova Kindelán, Jesús +2 more
core