Results 111 to 120 of about 167,252 (312)
Applied SciencesReproducing severe emission driving scenarios on a chassis dynamometer enables the systematic calibration of real driving emissions (RDE) under laboratory conditions.
Yang Chen +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Humanities & Social Sciences CommunicationsStandard driving cycles are commonly used to assess vehicle performance and to design and optimize vehicle powertrains. However, these standard driving cycles lack some details, especially regarding slopes, curves, traffic variability, or weather ...
Petr Hajduk +6 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Interleukins drive the cell cycle
The Journal of Cell Biology, 2005 Cytokines control the number of lymphocytes in the body. Too many cytokines can lead to lymphoma; an absence to immunodeficiency. And while it is broadly known that cytokines, like IL-3 and IL-7, block apoptosis, it is less well-recognized that they promote cell proliferation. On [page 755][1],
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
World Electric Vehicle JournalStandardized driving cycles often inadequately represent the driving patterns specific to a particular city, and variations in vehicle types within the same city further contribute to discrepancies in driving cycles.
Rui Liang, Junnan He, Pei Lu
doaj +1 more source
Methodology of constructing driving cycles by the synthesis [PDF]
, 2021 Akmal Mukhitdinov +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source