Results 81 to 90 of about 484,206 (263)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Factors driving water-sediment asynchrony in the Three Gorges Reservoir area

Shui kexue jinzhan
The asynchrony between water flow and sediment transport during the flood season in the Three Gorges Reservoir area is known to influence the sediment deposition distribution and sediment discharge operations in this region.
Xin LI, Ya LIU, Wei ZHANG, Xinyu PENG
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Analysis on the Evolution of Reclamation Space and Benefit-oriented Mechanism of Shenzhen from 1980 to 2020

Haiyang Kaifa yu guanli
Reclamation space, as an important part connecting land and sea, is a key link in land-sea coordination. Taking Shenzhen as an example, by combing the Landsat remote sensing image data from 1980 to 2020, analyzing the scale of reclamation and the change ...
Yun LI, Hongkun LIU, Yating FAN, Haoqin ZHENG, Zelin CHEN   +4 more
doaj  

Progress on nitrogen removal driving mechanism and influencing factors of Feammox

Gongye shui chuli
As a new type of wastewater treatment process, iron ammonia oxidation(Feammox) has attracted wide attention due to its advantages of low anaerobic energy consumption, no need to add organic carbon source and low sludge yield in the reaction process ...
ZHANG Xinlei, LIU Wenru
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Remote sensing assessment of shrub encroachment and its driving mechanisms in semi-arid grasslands

GIScience & Remote Sensing
Influenced by climate change and human activities, shrub encroachment in global arid and semi-arid grasslands profoundly affects ecosystem functions and livestock farming.
Ang Chen, Min Zhang, Cong Xu, Xiaoyu Xing, Dong Yang, Bin Xu, Xiuchun Yang   +6 more
doaj   +1 more source

Mechanisms for Driving Birkeland Currents

, 1975
QC ...
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Using ArcGIS and GeoDetector to evaluate the spatial differentiation characteristics and driving causes of Guangdong’s traditional villages

Journal of Asian Architecture and Building Engineering
This study examines 292 Chinese traditional villages in Guangdong, employing GIS and GeoDetector to reveal their spatial differentiation characteristics and formation mechanisms.
Mingming Yang, Zanariah Binti Jasmani
doaj   +1 more source