Results 51 to 60 of about 3,434,986 (241)

Lower Late Development Rate of Acute Respiratory Distress Syndrome in Patients with Lower Mechanical Power or Driving Pressure

Diagnostics
For patients on ventilation without acute respiratory distress syndrome (ARDS), there are, as yet, limited data on ventilation strategies. We hypothesized that driving pressure (DP) and mechanical power (MP) may play key roles for the late development of
Ya-Chi Lee, Pi-Hua Liu, Shih-Wei Lin, Chung-Chieh Yu, Chien-Ming Chu, Huang-Pin Wu   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Rolling out a new Driving Simulator Concept - Design and Challenges of Wheeled Mobile Driving Simulators

, 2021
Wheeled mobile driving simulators (WMDS) intend to cue the motion of road vehicles by moving a tire-bound, electrically driven, omnidirectional platform.
Albrecht, Torben, Winner, Hermann, Chen, Xing, Roßmeier, Willy, Ottensmeier, Meike, Plaettner, Stefan, Zöller, Chris, Tüschen, Thomas, Prokop, Günther, Lutwitzi, Melina   +9 more
core  

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The impact of pneumoperitoneum and steep Trendelenburg positioning on novel oxygenation and saturation indices in robot-assisted laparoscopic prostatectomies: A prospective observational study

Saudi Journal of Anaesthesia
Background: Robotic-assisted laparoscopic prostatectomy (RALP) poses challenges in ventilation and oxygenation due to steep Trendelenburg positioning and pneumoperitoneum.
Furkan Tontu, Hilal Akca, Cansu Kilinc Berktas, Sinan Asar, Funda Gumus Ozcan   +4 more
doaj   +1 more source

Impact of Different Tidal Volume Levels at Low Mechanical Power on Ventilator-Induced Lung Injury in Rats

Frontiers in Physiology, 2018
Tidal volume (VT) has been considered the main determinant of ventilator-induced lung injury (VILI). Recently, experimental studies have suggested that mechanical power transferred from the ventilator to the lungs is the promoter of VILI. We hypothesized
Lillian Moraes, Pedro L. Silva, Alessandra Thompson, Cintia L. Santos, Raquel S. Santos, Marcos V. S. Fernandes, Marcelo M. Morales, Vanessa Martins, Vanessa Martins, Vera L. Capelozzi, Marcelo G. de Abreu, Paolo Pelosi, Patricia R. M. Rocco   +12 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Individualized positive end-expiratory pressure guided by driving pressure in robot-assisted laparoscopic radical prostatectomy: a prospective, randomized controlled clinical trial

Frontiers in Medicine
BackgroundDespite the widespread use of lung-protective ventilation in general anesthesia, the optimal positive end-expiratory pressure (PEEP) remains uncertain.
Yanfang Luo, Siyu Qin, Mengxiao Liu, Qian Shen, Ran An, Yan Jiang   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source