Results 41 to 50 of about 4,857 (187)

Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications

open access: yesBMC Medicine, 2022
Background Medical cannabinoids differ in their pharmacology and may have different treatment effects. We aimed to conduct a pharmacology-based systematic review (SR) and meta-analyses of medical cannabinoids for efficacy, retention and adverse events ...
Ainhoa Bilbao, Rainer Spanagel
doaj   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh   +4 more
wiley   +1 more source

Exploring Clinical Similarities and Distinctions Between Gastroparesis and Functional Dyspepsia: A Propensity‐Matched Cohort Study

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
Despite overlapping upper gastrointestinal symptoms, gastroparesis and functional dyspepsia demonstrate distinct population‐level symptom patterns, with nausea, vomiting, and bloating predominating in gastroparesis and epigastric pain in functional dyspepsia.
Sameer Rao   +7 more
wiley   +1 more source

High‐Throughput Screening Using the Self‐Controlled Tree‐Based Scan Statistic to Identify Medications Associated With Hospitalization for Severe Acute Liver Injury

open access: yesPharmacoepidemiology and Drug Safety, Volume 34, Issue 12, December 2025.
ABSTRACT Background Medications associated with acute liver injury (ALI) are primarily identified by case reports. High‐throughput screening of real‐world data could be leveraged to detect hepatotoxicity signals. Objective To apply tree‐based scan statistics in real‐world data to identify drugs associated with hospitalization for severe ALI among ...
Vincent Lo Re III   +5 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Dronabinol oral solution in the management of anorexia and weight loss in AIDS and cancer

open access: yesTherapeutics and Clinical Risk Management, 2018
Melissa E Badowski, Paa Kwesi Yanful Section of Infectious Diseases Pharmacotherapy, Department of Pharmacy Practice, University of Illinois at Chicago, College of Pharmacy, Chicago, IL, USA Abstract: The true incidence of anorexia secondary to human ...
Badowski ME, Yanful PK
doaj  

Supportive Care in Cancer Cachexia: Meeting the Unmet Need

open access: yesAsian Pacific Journal of Cancer Care, 2022
Cachexia is characterized by loss of appetite, weight loss and tissue wasting, accompanied by a decrease in muscle mass and adipose tissue, affecting approximately 50% of cancer patients and contributes to decreased quality of life of patients, reduced ...
Abhishek Shankar   +9 more
doaj   +1 more source

Endocannabinoid System and the Role of Medical Cannabis in Treating Spasticity: A Narrative Review

open access: yesIatreia
To date, over 500 phytocannabinoids have been identified from the Cannabis sativa plant, among which ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most significant.
Navarro, Cristian Eduardo
doaj   +1 more source

Repositioning Cannabinoids and Terpenes as Novel EGFR-TKIs Candidates for Targeted Therapy Against Cancer: A virtual screening model using CADD and biophysical simulations

open access: yesHeliyon, 2023
This study examines the potential of Cannabis sativa L. plants to be repurposed as therapeutic agents for cancer treatment through designing of hybrid Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). A set of 50 phytochemicals was
Ossama Daoui   +4 more
doaj   +1 more source

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