Results 31 to 40 of about 5,508 (182)

Cannabis therapy in neurological disorders: Recent advances and perspectives [PDF]

Romanian Journal of Pharmaceutical Practice, 2020
Both phytocannabinoids (Δ9-tetrahydrocannabinol, cannabidiol) and synthetic derivatives (nabilone, dronabinol) showed therapeutic benefits in some neurological disorders.
Alexandru Mandici, Daniel Cojocariu, Anca Miron   +2 more
doaj   +1 more source

Grinding and Fractionation during Distillation Alter Hemp Essential Oil Profile and Its Antimicrobial Activity

Molecules, 2020
The hypothesis of this study was that we can modify the essential oil (EO) profile of hemp (Cannabis sativa L.) and obtain fractions with differential composition and antimicrobial activity.
Valtcho D. Zheljazkov, Vladimir Sikora, Ivanka B. Semerdjieva, Miroslava Kačániová, Tess Astatkie, Ivayla Dincheva   +5 more
doaj   +1 more source

Case Report: Secondary bilateral parkinsonism and dystonia treated with dronabinol [version 3; peer review: 2 approved]

F1000Research, 2021
Drug abuse may damage basal ganglia that are essential for planning and execution of movements. We report about the case of a 38-year old patient with ischemic lesions of the basal ganglia presenting with bilateral painful dystonia and parkinsonism ...
Natalia Szejko, Florian Burger, Victoria Sidoroff, Gregor K. Wenning   +3 more
doaj   +1 more source

Cannabinoids in the Treatment of Cannabis Use Disorder: Systematic Review of Randomized Controlled Trials

Frontiers in Psychiatry, 2022
BackgroundThe prevalence of cannabis use and cannabis use disorders (CUD) has significantly increased over time. However, there are no approved pharmacological treatments for CUD.
Caroline Vuilleumier, Norbert Scherbaum, Udo Bonnet, Udo Bonnet, Patrik Roser, Patrik Roser   +5 more
doaj   +1 more source

Industrial, CBD, and Wild Hemp: How Different Are Their Essential Oil Profile and Antimicrobial Activity?

Molecules, 2020
Hemp (Cannabis sativa L.) is currently one of the most controversial and promising crops. This study compared nine wild hemp (C. sativa spp. spontanea V.) accessions with 13 registered cultivars, eight breeding lines, and one cannabidiol (CBD) hemp ...
Valtcho D. Zheljazkov, Vladimir Sikora, Ivayla Dincheva, Miroslava Kačániová, Tess Astatkie, Ivanka B. Semerdjieva, Dragana Latkovic   +6 more
doaj   +1 more source

Identification of Potential Distinguishing Markers for the Use of Cannabis-Based Medicines or Street Cannabis in Serum Samples

Metabolites, 2021
Increasing prescription numbers of cannabis-based medicines raise the question of whether uptake of these medicines can be distinguished from recreational cannabis use. In this pilot study, serum cannabinoid profiles after use of cannabis-based medicines
Anne Scheunemann, Katrin Elsner, Tanja Germerott, Sergiu Groppa, Cornelius Hess, Isabelle Miederer, Alicia Poplawski, Jörg Röhrich   +7 more
doaj   +1 more source

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

Phytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco, Daniela Fortunato Rêgo, Carolina de Oliveira Cruz Latorraca, Marco Aurelio de Carvalho Nascimento, André Bastos Daher, Rachel Riera   +5 more
wiley   +1 more source

A single-dose comparative bioavailability study of dronabinol oral solution versus dronabinol capsules in healthy volunteers.

, 2016
198 Background: The capsule formulation of dronabinol, a pharmaceutical tetrahydrocannabinol (THC), is approved for anorexia associated with weight loss in patients with AIDS and for cancer chemotherapy-associated nausea/vomiting in patients with ...
Varun Khurana, Christina Cognata Smith, Santosh Vetticaden, Neha Parikh, William G. Kramer   +4 more
core   +1 more source

Comparative effectiveness, safety and acceptability of pharmacological and psychosocial interventions for the treatment of cannabis use disorder: A network meta‐analysis

Addiction, EarlyView.
Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka, Francesca Spiga, Tom P. Freeman, Suzanne Nielsen, Jelena Savović, Julian P. T. Higgins, Deborah M. Caldwell   +6 more
wiley   +1 more source

Effect of food on the pharmacokinetics of dronabinol oral solution versus dronabinol capsules in healthy volunteers.

, 2016
199 Background: Dronabinol, a pharmaceutical tetrahydrocannabinol (THC), capsule is approved for anorexia associated with weight loss in patients with AIDS and for cancer chemotherapy-induced nausea/vomiting in patients with inadequate response to ...
Varun Khurana, Christina Cognata Smith, D. Alexander Oh, Santosh Vetticaden, Neha Parikh   +4 more
core   +1 more source