Therapeutic Potential of Dronabinol: A Systematic Review of Human Trials [PDF]
Dronabinol is an isomer of tetrahydrocannabinol that seems to have potential for both somatic and psychiatric disorders treatment. The purpose of this review is to provide an overview of collected articles with emphasis on the efficacy and safety of ...
Julia Lewandowska +2 more
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Pronounced State-Level Disparities in Prescription of Cannabinoids to Medicaid Patients
Introduction: Dronabinol is approved in the USA for chemotherapy-induced nausea as well as vomiting and HIV-induced anorexia, while cannabidiol is primarily approved for childhood epileptic disorders Lennox-Gastaut and Dravet syndrome.
Edward Y. Liu +2 more
doaj +1 more source
DMSO potentiates the suppressive effect of dronabinol on sleep apnea and REM sleep in rats
Introduction Dimethyl sulfoxide (DMSO) is an amphipathic molecule with innate biological activity that also is used to dissolve both polar and nonpolar compounds in preclinical and clinical studies.
Michael W. Calik, David W. Carley
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Background: Cannabis may offer therapeutic benefits to patients with advanced cancer not responding adequately to conventional palliative treatment. However, tolerability is a major concern.
Ditte Buchwald +8 more
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Matched pilot study examining cannabis-based dronabinol for acute pain following traumatic injury
Background To determine whether adjunctive dronabinol, a licensed form of delta-9-tetrahydrocannabinol, reduces opioid consumption when used off-label for managing acute pain following traumatic injury.Methods This matched cohort study included patients ...
Kristin Salottolo +5 more
doaj +1 more source
Delta-9-tetrahydrocannabinol (Δ9-THC) and other cannabinoids present in cannabis (marijuana) have been shown to affect the normal inhibitory pathways that influence nociception in humans.
Claire Swartwood +3 more
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Caracterización de la problemática del uso terapéutico del Aceite de Cannabis en Córdoba, Argentina
El uso terapéutico del aceite de “cannabis” es una problemática social que pone en tensión aspectos legales, sanitarios, científicos y culturales. La dificultad en el acceso genera un vacío aprovechado por el mercado ilegal, al que recurren pacientes y ...
Pablo Gabriel Manzo +9 more
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Cannabinoid type 1 and type 2 receptor antagonists prevent attenuation of serotonin-induced reflex apneas by dronabinol in Sprague-Dawley rats. [PDF]
The prevalence of obstructive sleep apnea (OSA) in Americans is 9% and increasing. Increased afferent vagal activation may predispose to OSA by reducing upper airway muscle activation/patency and disrupting respiratory rhythmogenesis.
Michael W Calik, David W Carley
doaj +1 more source
Acetylcholinesterase Inhibitory Activity of Standardized Cannabinoids-rich Fractions [PDF]
Background: Since cannabis has been legally allowed for medicinal purposes in many countries, it has become the most interesting issue, particularly in neurologic disorders, such as Alzheimer’s disease (AD).
Wiwit Suttithumsatid +4 more
doaj
Unexpected improvement of hyperhidrosis with cannabidiol [PDF]
Hyperhidrosis is characterized by excessive sweating and it affects almost 5% of the population. The affected age group is wide, and it can affect from children to elderlies. There are two types of hyperhidrosis: generalized and focal.
Rubens Pitliuk +2 more
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