Bioavailability study of dronabinol oral solution versus dronabinol capsules in healthy volunteers
Neha Parikh,1 William G Kramer,2 Varun Khurana,1 Christina Cognata Smith,1 Santosh Vetticaden,1 1INSYS Therapeutics, Inc., Chandler, AZ, USA; 2Kramer Consulting LLC, North Potomac, MD, USA Background: Dronabinol, a pharmaceutical Δ-9 ...
Parikh N +4 more
doaj +6 more sources
Proof of Concept Trial of Dronabinol in Obstructive Sleep Apnea [PDF]
Study Objective: Animal data suggest that ∆9-TetraHydroCannabinol (∆9THC) stabilizes autonomic output during sleep, reduces spontaneous sleep-disordered breathing and blocks serotonin-induced exacerbation of sleep apnea.
Bharati ePrasad +2 more
doaj +5 more sources
Delta-9-tetrahydrocannabinol (Δ9-THC) and other cannabinoids present in cannabis (marijuana) have been shown to affect the normal inhibitory pathways that influence nociception in humans.
Claire Swartwood +3 more
doaj +2 more sources
Cannabinoid type 1 and type 2 receptor antagonists prevent attenuation of serotonin-induced reflex apneas by dronabinol in Sprague-Dawley rats. [PDF]
The prevalence of obstructive sleep apnea (OSA) in Americans is 9% and increasing. Increased afferent vagal activation may predispose to OSA by reducing upper airway muscle activation/patency and disrupting respiratory rhythmogenesis.
Michael W Calik, David W Carley
doaj +2 more sources
Treatment of Chronic Intractable Neuropathetic Pain with Dronabinol: Case Report of Two Adolescents [PDF]
OBJECTIVE: To evaluate the effectiveness of dronabinol for the treatment of neuropathic pain refractory to previous treatment.
Zvia Rudich +3 more
doaj +4 more sources
D Alexander Oh, Neha Parikh, Varun Khurana, Christina Cognata Smith, Santosh VetticadenINSYS Therapeutics, Inc., Chandler, AZ, USA Abstract: Dronabinol is a pharmaceutical tetrahydrocannabinol originally developed as an oral capsule.
Oh DA +4 more
doaj +1 more source
Treating nightmares in posttraumatic stress disorder with dronabinol: study protocol of a multicenter randomized controlled study (THC PTSD-trial) [PDF]
Background Distressing nightmares are a core symptom of posttraumatic stress disorder (PTSD) and contribute to psychiatric comorbidity, impaired physical health and decreased social functioning.
Stefan Roepke +9 more
doaj +3 more sources
Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics
Megan Brafford May,1 Ashley E Glode2 1Department of Pharmacy, Baptist Health Lexington, Lexington, KY, USA; 2Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus ...
May MB, Glode AE
doaj +1 more source
Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS
Melissa E Badowski,1 Sarah E Perez2 1Department of Pharmacy Practice, Section of Infectious Diseases Pharmacotherapy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; 2Infectious Diseases Clinic, Tufts Medical Center, Boston, MA,
Badowski ME, Perez SE
doaj +1 more source
Evaluation of morphine, methadone, digoxin, and dronabinol poisoning during the years 2017 to 2019 in Ilam, Iran [PDF]
Background: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam.
Kourosh Saki +8 more
doaj +2 more sources

