Impact of Low-Dose Dronabinol Therapy on Cognitive Function in Cancer Patients Receiving Palliative Care: A Case-Series Intervention Study [PDF]
Palliative Medicine Reports, 2023 Background: Cannabis may offer therapeutic benefits to patients with advanced cancer not responding adequately to conventional palliative treatment. However, tolerability is a major concern.
Ditte Buchwald +8 more
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Brain Sciences, 2020 Delta-9-tetrahydrocannabinol (Δ9-THC) and other cannabinoids present in cannabis (marijuana) have been shown to affect the normal inhibitory pathways that influence nociception in humans.
Claire Swartwood +3 more
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Clinical Pharmacology: Advances and Applications, 2017 D Alexander Oh, Neha Parikh, Varun Khurana, Christina Cognata Smith, Santosh VetticadenINSYS Therapeutics, Inc., Chandler, AZ, USA Abstract: Dronabinol is a pharmaceutical tetrahydrocannabinol originally developed as an oral capsule.
Oh DA +4 more
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Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics
Cancer Management and Research, 2016 Megan Brafford May,1 Ashley E Glode2 1Department of Pharmacy, Baptist Health Lexington, Lexington, KY, USA; 2Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus ...
May MB, Glode AE
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Treatment of Chronic Intractable Neuropathetic Pain with Dronabinol: Case Report of Two Adolescents [PDF]
Pain Research and Management, 2003 OBJECTIVE: To evaluate the effectiveness of dronabinol for the treatment of neuropathic pain refractory to previous treatment.
Zvia Rudich +3 more
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Cannabinoid type 1 and type 2 receptor antagonists prevent attenuation of serotonin-induced reflex apneas by dronabinol in Sprague-Dawley rats. [PDF]
PLoS ONE, 2014 The prevalence of obstructive sleep apnea (OSA) in Americans is 9% and increasing. Increased afferent vagal activation may predispose to OSA by reducing upper airway muscle activation/patency and disrupting respiratory rhythmogenesis.
Michael W Calik, David W Carley
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Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS
HIV/AIDS: Research and Palliative Care, 2016 Melissa E Badowski,1 Sarah E Perez2 1Department of Pharmacy Practice, Section of Infectious Diseases Pharmacotherapy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; 2Infectious Diseases Clinic, Tufts Medical Center, Boston, MA,
Badowski ME, Perez SE
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Bedtime tetrahydrocannabinol ingestion reduces morning orthostatic cardiovascular reactivity in adults: An exploratory study. [PDF]
Physiol RepAbstract Acute cannabis use and its primary psychoactive constituent tetrahydrocannabinol (THC) can induce postural dizziness, indicating increased risk of orthostatic instability. However, it is unknown if vulnerabilities persist the morning after bedtime THC consumption.
Gonzalez JE +8 more
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DMSO potentiates the suppressive effect of dronabinol on sleep apnea and REM sleep in rats
Journal of Cannabis Research, 2023 Introduction Dimethyl sulfoxide (DMSO) is an amphipathic molecule with innate biological activity that also is used to dissolve both polar and nonpolar compounds in preclinical and clinical studies.
Michael W. Calik, David W. Carley
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Matched pilot study examining cannabis-based dronabinol for acute pain following traumatic injury
Trauma Surgery & Acute Care Open, 2020 Background To determine whether adjunctive dronabinol, a licensed form of delta-9-tetrahydrocannabinol, reduces opioid consumption when used off-label for managing acute pain following traumatic injury.Methods This matched cohort study included patients ...
Kristin Salottolo +5 more
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