The Safety of Dronabinol and Nabilone: A Systematic Review and Meta-Analysis of Clinical Trials
Pharmaceuticals, 2022 Dronabinol, a natural cannabinoid, and its semi-synthetic derivative, nabilone, are marketed as medicines in several countries. The aim of our work was to systematically evaluate the frequency of adverse events related to dronabinol or nabilone treatment
Szabolcs Kiss +2 more
exaly +4 more sources
Dronabinol oral solution in the management of anorexia and weight loss in AIDS and cancer
Therapeutics and Clinical Risk Management, 2018 Melissa E Badowski, Paa Kwesi Yanful Section of Infectious Diseases Pharmacotherapy, Department of Pharmacy Practice, University of Illinois at Chicago, College of Pharmacy, Chicago, IL, USA Abstract: The true incidence of anorexia secondary to human ...
exaly +3 more sources
Reducing severe breathlessness with dronabinol in the group of patients with severe and very severe chronic obstructive pulmonary disease (BONG): a randomised, double-blinded, placebo-controlled, crossover study in an outpatient clinic in Denmark – a study protocol [PDF]
BMJ OpenIntroduction Cannabis-based medicine may alleviate breathlessness. This study will investigate whether dronabinol, a synthetic form of Δ9-tetrahydrocannabinol (Δ9-THC), reduces breathlessness in patients with severe and very severe chronic obstructive ...
Anders Løkke +5 more
doaj +3 more sources
Impact of Low-Dose Dronabinol Therapy on Cognitive Function in Cancer Patients Receiving Palliative Care: A Case-Series Intervention Study [PDF]
Palliative Medicine Reports, 2023 Background: Cannabis may offer therapeutic benefits to patients with advanced cancer not responding adequately to conventional palliative treatment. However, tolerability is a major concern.
Ditte Buchwald +8 more
doaj +3 more sources
A pilot study of dronabinol for the treatment of pain in sickle cell disease [PDF]
Pilot and Feasibility StudiesBackground Many adults living with sickle cell disease (SCD) suffer from chronic pain, turning to cannabis for relief. However, there are few studies that examine the efficacy of cannabis in treating pain associated with SCD.
Susanna A. Curtis +5 more
doaj +2 more sources
Investigating the effects of cannabinoids for the reduction of inflammation and sickle cell disease pain (CRISP); A protocol for a randomized double-blind placebo-controlled study. [PDF]
PLoS ONESickle Cell Disease (SCD) is a hemoglobinopathy affecting millions of people globally. Pain, both acute and chronic, affects over half of those living with SCD, but treatment of chronic pain is an ongoing challenge.
Jordan Bellis +8 more
doaj +2 more sources
Rastafarianism: When Religious Beliefs Conflict With Medical Necessity—A Case Report and Review of the Literature Around an Ethically Complicated Case [PDF]
Case Reports in PsychiatryDiscussion: This case exemplifies the complexities of clinical care when religious beliefs conflict with medical necessity. We discuss the limited indications for dronabinol and potential adverse effects on delirium’s behavioral symptoms.
Matthew Flick +2 more
doaj +2 more sources
Therapeutic Potential of Dronabinol: A Systematic Review of Human Trials [PDF]
Farmacja Polska, 2021 Dronabinol is an isomer of tetrahydrocannabinol that seems to have potential for both somatic and psychiatric disorders treatment. The purpose of this review is to provide an overview of collected articles with emphasis on the efficacy and safety of ...
Julia Lewandowska +2 more
doaj +1 more source
Pronounced State-Level Disparities in Prescription of Cannabinoids to Medicaid Patients
Medical Cannabis and Cannabinoids, 2023 Introduction: Dronabinol is approved in the USA for chemotherapy-induced nausea as well as vomiting and HIV-induced anorexia, while cannabidiol is primarily approved for childhood epileptic disorders Lennox-Gastaut and Dravet syndrome.
Edward Y. Liu +2 more
doaj +1 more source
DMSO potentiates the suppressive effect of dronabinol on sleep apnea and REM sleep in rats
Journal of Cannabis Research, 2023 Introduction Dimethyl sulfoxide (DMSO) is an amphipathic molecule with innate biological activity that also is used to dissolve both polar and nonpolar compounds in preclinical and clinical studies.
Michael W. Calik, David W. Carley
doaj +1 more source