Results 101 to 110 of about 641,662 (284)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Enhancing Throughput of Combinatorial Droplet Devices via Droplet Bifurcation, Parallelized Droplet Fusion, and Parallelized Detection

Micromachines, 2015
Combinatorial droplet microfluidic devices with programmable microfluidic valves have recently emerged as a viable approach for performing multiplexed experiments in microfluidic droplets.
Kuangwen Hsieh, Helena C. Zec, Polly C. Ma, Tushar D. Rane, Tza-Huei Wang   +4 more
doaj   +1 more source

Evaporation-induced sintering of liquid metal droplets with biological nanofibrils for flexible conductivity and responsive actuation

Nature Communications, 2019
Liquid metal (LM) droplets show the superiority in coalescing into integral liquid conductors applicable in flexible and deformable electronics. However, the large surface tension, oxide shells and poor compatibility with most other materials may prevent
Xian-Kai Li, Ming-Jie Li, Jie Xu, Jun You, Zhi-Qin Yang, Chao-Xu Li   +5 more
semanticscholar   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Monodisperse Water-in-Oil-in-Water (W/O/W) Double Emulsion Droplets as Uniform Compartments for High-Throughput Analysis via Flow Cytometry

, 2013
Here we report the application of monodisperse double emulsion droplets, produced in a single step within partially hydrophilic/partially hydrophobic microfluidic devices, as defined containers for quantitative flow cytometric analysis.
Wolfgang-Andreas C. Bauer, Clemens Kaminski, Bauer, Wolfgang-Andreas, Kaminski, Clemens, Jing Yan, Huck, Wilhelm, Wolfgang-Andreas Bauer, Clemens F. Kaminski, Hollfelder, Florian, Wilhelm Huck, Martin Fischlechner, Florian Hollfelder, Yan, Jing, Wilhelm T. S. Huck, Fischlechner, Martin   +14 more
core   +1 more source

Topological transport of a classical droplet in a lattice of time

Natural Sciences
Thouless charge pumps are quantum mechanical devices whose operation relies on topology. They provide the means for transporting quantum matter in space lattices with a single quantum precision.
Tapio Simula, Niels Kjærgaard, Tilman Pfau   +2 more
doaj   +1 more source

Operation of Droplet-Microfluidic Devices with a Lab Centrifuge

Micromachines, 2016
Microfluidic devices are valuable for a variety of biotechnology applications, such as synthesizing biochemical libraries, screening enzymes, and analyzing single cells. However, normally, the devices are controlled using specialized pumps, which require
Noorsher Ahmed, David Sukovich, Adam R. Abate   +2 more
doaj   +1 more source

Electro-Hydrodynamics of Emulsion Droplets: Physical Insights to Applications

Micromachines, 2020
The field of droplet electrohydrodynamics (EHD) emerged with a seminal work of G.I. Taylor in 1966, who presented the so-called leaky dielectric model (LDM) to predict the droplet shapes undergoing distortions under an electric field.
Muhammad Salman Abbasi, Ryungeun Song, Seongsu Cho, Jinkee Lee   +3 more
doaj   +1 more source

Physico-chemical characteristics of evaporating respiratory fluid droplets

Journal of the Royal Society Interface, 2018
The detailed physico-chemical characteristics of respiratory droplets in ambient air, where they are subject to evaporation, are poorly understood. Changes in the concentration and phase of major components in a droplet—salt (NaCl), protein (mucin) and ...
Eric P. Vejerano, L. Marr
semanticscholar   +1 more source