Results 71 to 80 of about 234,073 (269)
Micromachines, 2015 Combinatorial droplet microfluidic devices with programmable microfluidic valves have recently emerged as a viable approach for performing multiplexed experiments in microfluidic droplets.
Kuangwen Hsieh +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Topological transport of a classical droplet in a lattice of time
Natural SciencesThouless charge pumps are quantum mechanical devices whose operation relies on topology. They provide the means for transporting quantum matter in space lattices with a single quantum precision.
Tapio Simula +2 more
doaj +1 more source
Operation of Droplet-Microfluidic Devices with a Lab Centrifuge
Micromachines, 2016 Microfluidic devices are valuable for a variety of biotechnology applications, such as synthesizing biochemical libraries, screening enzymes, and analyzing single cells. However, normally, the devices are controlled using specialized pumps, which require
Noorsher Ahmed +2 more
doaj +1 more source
Electro-Hydrodynamics of Emulsion Droplets: Physical Insights to Applications
Micromachines, 2020 The field of droplet electrohydrodynamics (EHD) emerged with a seminal work of G.I. Taylor in 1966, who presented the so-called leaky dielectric model (LDM) to predict the droplet shapes undergoing distortions under an electric field.
Muhammad Salman Abbasi +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A Flexible, Microfluidic, Dispensing System for Screening Drug Combinations
Micromachines, 2020 It is known that in many cases a combination of drugs is more effective than single-drug treatments both for reducing toxicity and increasing efficacy.
Mark Davies +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Қарағанды университетінің хабаршысы. Физика сериясыIn the present study, the processes of breakup, dispersion, and evaporation of gasoline droplets in a model combustion chamber under high turbulence reacting flow were investigated using modern computational modeling methods.
A.S. Askarova +5 more
doaj +1 more source