Results 181 to 190 of about 428,367 (405)

Design and construction of a new Drosophila species, D.synthetica, by synthetic regulatory evolution [PDF]

open access: yes, 2011
Here, I merge the principles of synthetic biology^1,2^ and regulatory evolution^3-11^ to create a new species^12-15^ with a minimal set of known elements.
Eduardo Moreno
core   +1 more source

Transgenerational Reproductive and Developmental Toxicity Induced by N‐Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT N‐Nitrosodimethylamine (NDMA) is a known water disinfection byproduct (DBP) characterized as a potent hepatotoxin, promutagen, and probable human carcinogen; this is because of the metabolites associated with its biotransformation. The metabolism of NDMA produces formaldehyde, another alkylating agent and DBP. Both compounds are generated from
Oscar Eduardo Tabares‐Mosquera   +3 more
wiley   +1 more source

CG-content log-ratio distributions of Caenorhabditis elegans and Drosophila melanogaster mirtrons [PDF]

open access: yesarXiv, 2013
Mirtrons are a special type of pre-miRNA which originate from intronic regions and are spliced directly from the transcript instead of being processed by Drosha. The splicing mechanism is better understood for the processing of mRNA for which was established that there is a characteristic CG content around splice sites.
arxiv  

Parallel Geographic Variation in Drosophila melanogaster

open access: yesGenetics, 2014
Drosophila melanogaster, an ancestrally African species, has recently spread throughout the world, associated with human activity. The species has served as the focus of many studies investigating local adaptation relating to latitudinal variation in non-
Josephine A. Reinhardt   +4 more
semanticscholar   +1 more source

Arsenic-containing hydrocarbons are toxic in the in vivo model Drosophila melanogaster.

open access: yesMetallomics, 2014
Arsenic-containing hydrocarbons (AsHC) constitute one group of arsenolipids that have been identified in seafood. In this first in vivo toxicity study for AsHCs, we show that AsHCs exert toxic effects in Drosophila melanogaster in a concentration range ...
S. Meyer   +8 more
semanticscholar   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Host condition and pathogen identity influence bacterial infection survival in the common eastern firefly, Photinus pyralis

open access: yesEcological Entomology, Volume 48, Issue 1, Page 90-101, February 2023., 2023
Fireflies in worse condition or collected later in the season had reduced survival relative to fireflies in better condition or collected earlier in the season. Serratia marcescens and Providencia rettgeri infections increased firefly mortality while Providencia sneebia, Pseudomonas aeruginosa, and Enterococcus faecalis infections did not. Abstract The
Sarah E. Lower   +5 more
wiley   +1 more source

Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster [PDF]

open access: yesarXiv, 2013
Sequencing of pools of individuals (Pool-Seq) represents a reliable and cost- effective approach for estimating genome-wide SNP and transposable element insertion frequencies. However, Pool-Seq does not provide direct information on haplotypes so that for example obtaining inversion frequencies has not been possible until now. Here, we have developed a
arxiv  

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