Results 201 to 210 of about 437,033 (326)

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

open access: yesThe FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast   +3 more
wiley   +1 more source

Forest type influence on Heliconia‐dipteran interaction networks

open access: yesInsect Conservation and Diversity, EarlyView.
Responses to forest type depended on the developmental stage of dipterans. Bract traits and forest type influenced larval abundance, but forest type had no impact on adult alpha and beta diversity. Heliconia‐dipteran interaction networks showed a nested pattern for both forest types.
Diana M. Méndez‐Rojas   +5 more
wiley   +1 more source

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

open access: yesInsect Molecular Biology, EarlyView.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin   +4 more
wiley   +1 more source

Identification of <i>Drosophila melanogaster</i> as a model organism in COPD research. [PDF]

open access: yesFront Immunol
Zhang Y   +9 more
europepmc   +1 more source

Genome and transcriptome‐based identification and expression profiling of chemosensory gene families across developmental stages and tissues in Sirex noctilio (Hymenoptera: Siricidae)

open access: yesInsect Molecular Biology, EarlyView.
The first draft genome of Sirex noctilio was produced. Fifteen S. noctilio transcriptomes were sequenced to study chemosensory gene expression patterns. SnocOR16 and SnocSNMP1 displayed tissue‐ and sex‐specific expression patterns. Abstract The Sirex woodwasp (Sirex noctilio; Hymenoptera: Siricidae) is among the most destructive invasive pests ...
Alisa Postma   +21 more
wiley   +1 more source

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

open access: yesJournal of Integrative Plant Biology, EarlyView.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang   +7 more
wiley   +1 more source

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