Distinctive gene expression in the reduced first thoracic legs of a nymphalid butterfly
Transcriptome analysis reveals that the small non‐walking front legs of a butterfly have distinct gene expression to the four walking legs. Reduced front legs express a gene with putative mechanosensory roles, a blue‐sensitive opsin and two homeobox genes.
Asia E. Hoile +2 more
wiley +1 more source
Drosophila melanogaster mitigates gastro-oral infections by stimulating pathogen expulsion. [PDF]
Verma S +3 more
europepmc +1 more source
Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez +1 more
wiley +1 more source
Luteolin promotes healthy aging in adult females but shortens lifespan after embryonic exposure in <i>Drosophila melanogaster</i>. [PDF]
Wu Q +7 more
europepmc +1 more source
Genome‐wide systematic annotation identified 81 odorant receptors (ORs) and 49 odorant‐binding proteins (OBPs) in the tobacco budworm, Chloridea virescens. Phylogenetic analyses revealed chemosensory gene diversification in Heliothinae and extensive lineage‐specific duplications in C.
Rong Guo, Boyang Ni, Megan L. Fritz
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Exploring the bioavailability and bioactivity of thiamine versus allithiamine: studies in <i>Drosophila melanogaster</i> and mice. [PDF]
Nevermann S +9 more
europepmc +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Mutual Influence of Sucralose and Bisphenol A on Biological and Neurobehavioral Action in <i>Drosophila melanogaster</i>. [PDF]
Miranda N +4 more
europepmc +1 more source

