Results 221 to 230 of about 272,901 (277)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, Volume 600, Issue 17, Page 2420-2436, September 2026.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sex-Specific Regulation of the Turandot Gene Family Modulates Temperature-Dependent Lifespan in Drosophila melanogaster. [PDF]

Aging Cell
Hoffman JM, Lasher AT, Fitch MP, Austad SN, Sun LY.   +4 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, Volume 600, Issue 17, Page 2579-2614, September 2026.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Individuality across environmental context in <i>Drosophila melanogaster</i>. [PDF]

Elife
Mathejczyk TF, Knief C, Haidar MA, Freitag F, McClary T, Wernet MF, Linneweber GA.   +6 more
europepmc   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

The impact of exercise on protein levels in Drosophila melanogaster. [PDF]

Biol Open
Walts JC, Dave AA, Riddle NC.
europepmc   +1 more source

The Extracellular Matrix Proteins Pericardin and Lonely Heart Modulate the Directionality of Heart Contractions in Infected Mosquitoes

Archives of Insect Biochemistry and Physiology, Volume 123, Issue 1, September 2026.
Pericardin and Lonely heart, which are components of the cardiac extracellular matrix, influence the direction in which the heart of mosquitoes propels hemolymph (blood). ABSTRACT The cardiac extracellular matrix provides structural support to the primary circulatory organ of an insect: a dorsal vessel that is divided into an aorta in the thorax and a ...
Shabbir Ahmed, Puspa K. Shah, Julián F. Hillyer   +2 more
wiley   +1 more source

Knockouts of Sulfur Metabolism Genes Induce Chronic Inflammation and Immune Dysregulation in <i>Drosophila melanogaster</i>. [PDF]

Antioxidants (Basel)
Shilova V, Rezvykh A, Aristova V, Davletshin A, Andreeva A, Ponomareva K, Garbuz D, Evgen'ev M, Zatsepina O.   +8 more
europepmc   +1 more source

Effects of Alpha Particle Exposure on Genetic Stability and Morphogenesis in <i>Drosophila melanogaster</i>. [PDF]

Biology (Basel)
Biyasheva Z, Zaripova Y, Lovinskaya A, Dyachkov V, Yushkov A.   +4 more
europepmc   +1 more source