Results 191 to 200 of about 437,033 (326)

Cost of parasite exposure depends on host ontogeny 寄生接觸的代價依賴於宿主發育階段

open access: yesEcological Entomology, EarlyView.
The cost of parasite exposure varies across host developmental stages, demonstrating that ontogeny influences the expression of non‐consumptive effects (NCEs). Mite exposure resulted in consumptive effects in fly eggs and NCEs in early‐stage pupae; mite longevity was comparable when provisioned with pupae or water but increased when provisioned with ...
Lisa R. MacLeod   +2 more
wiley   +1 more source

Clock mutants of Drosophila melanogaster.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1971
R. Konopka, S. Benzer
semanticscholar   +1 more source

Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila

open access: yesThe FEBS Journal, EarlyView.
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause   +5 more
wiley   +1 more source

Proteostasis of organelles in aging and disease

open access: yesThe FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi   +5 more
wiley   +1 more source

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

open access: yesEMBO Journal, 2001
Sayda M. Elbashir   +4 more
semanticscholar   +1 more source

KU80 suppresses endonuclease G activity to preserve genomic integrity

open access: yesThe FEBS Journal, EarlyView.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan   +8 more
wiley   +1 more source

Genetic dissection reveals distinct contributions of the eS31 N‐terminal domain to translational accuracy in Saccharomyces cerevisiae

open access: yesThe FEBS Journal, EarlyView.
The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao   +3 more
wiley   +1 more source

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