Interactions between dorsal and helix-loop-helix proteins initiate the differentiation of the embryonic mesoderm and neuroectoderm in Drosophila. [PDF]
Sergio González‐Crespo+1 more
openalex +1 more source
Neurodegenerative and Neurodevelopmental Roles for Bulk Lipid Transporters VPS13A and BLTP2
Abstract Background Bridge‐like lipid transfer proteins (BLTPs) mediate bulk lipid transport at membrane contact sites. Mutations in BLTPs are linked to both early‐onset neurodevelopmental and later‐onset neurodegenerative diseases, including movement disorders.
Sarah D. Neuman+4 more
wiley +1 more source
Inwardly rectifying potassium channels: Critical insights for insect species and Apis mellifera. [PDF]
Sourisseau F+3 more
europepmc +1 more source
The Drosophila l(2)35Ba/nocA gene encodes a putative Zn finger protein involved in the development of the embryonic brain and the adult ocellar structures. [PDF]
P Y Cheah+5 more
openalex +1 more source
Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles+29 more
wiley +1 more source
Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC). [PDF]
Viswanatha R+8 more
europepmc +1 more source
Genetic investigation of cAMP-dependent protein kinase function in Drosophila development. [PDF]
Mary Ellen Lane, Daniel Kalderon
openalex +1 more source
Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila
W. Swanson+4 more
semanticscholar +1 more source
ABSTRACT Background Congenital mirror movement disorders (CMMs) are clinically and genetically heterogeneous in human patients. CMMs have not been documented to occur spontaneously in animals. Objective The objective of this work was to document the first case of CMMs spontaneously occurring in Weimaraner dogs and to identify the underlying genetic ...
Cleo Schwarz+11 more
wiley +1 more source