Results 91 to 100 of about 2,190,373 (263)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Pantoprazole – safety in drug-drug interaction
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012 The aim of review. To carry out comparative analysis of metabolic pathways of proton pump inhibitors (PPI), to determine the agent with lowest effect on activity of cytochrome CYP2C19 isoenzyme for improvement of safety of combined treatment by ...
E. V. Shikh, D. A. Sychev
doaj
DDIGIP: predicting drug-drug interactions based on Gaussian interaction profile kernels
BMC Bioinformatics, 2019 Background A drug-drug interaction (DDI) is defined as a drug effect modified by another drug, which is very common in treating complex diseases such as cancer.
Cheng Yan +4 more
doaj +1 more source
Clozapine treatment in patients living in the community [PDF]
, 2015 OBJECTIVE: The aim of this study was to assess clozapine treatment in the local community with respect to patient monitoring during dispensing, patient compliance through prescription refills, presence of any other existing co-morbidities and ...
Azzopardi, Lilian M., Schembri, Karl
core
Evaluation of the surface chemistry and drug-polymer interaction of semi-crystalline micro-particles for the development of controlled release formulations [PDF]
, 2017 This research work explores the surface chemistry and drug-polymer interaction in the manufactured controlled release micro-particles. Isoniazid (INH) was used as a model anti-tubercular drug while Eudragit® S100 (S100), Eudragit® L100-55 based co ...
Chowdhry, Babur Z +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Drug-Drug Interaction Management in Hepatitis C Treatment
Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2018 “Direct acting antivirals” cure over 99% in the course of the disease as a recent breakthrough treatment method in hepatitis C treatment. Possible drug-drug interactions should not be overlooked.
İrem Akdemir Kalkan +3 more
doaj +1 more source
Drug–drug interaction analysis: Antituberculosis drugs versus antiretroviral drugs
Biomedical and Biotechnology Research Journal, 2019 Background: Human immunodeficiency virus (HIV) infection is an important public health globally. An important concomitant medical disorder among HIV-infected patients is tuberculosis. The management of concurrent infection between HIV and tuberculosis is
Won Sriwijitalai, Viroj Wiwanitkit
doaj +1 more source