Results 31 to 40 of about 1,977,916 (307)

Insights into CYP2B6-mediated drug–drug interactions

Acta Pharmaceutica Sinica B, 2016
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. The discovery of multiple important substrates of CYP2B6 as well as polymorphic differences has sparked increasing interest in the ...
William D. Hedrich, Hazem E. Hassan, Hongbing Wang   +2 more
doaj   +1 more source

MOESM2 of Potential drugâ drug interactions among elderly patients admitted to medical ward of Ayder Referral Hospital, Northern Ethiopia: a cross sectional study

, 2016
Additional file 2. STROBE Statementâ checklist of items that should be included in reports of observational studies.
Fantaye Teka, Gebrehiwot Teklay, Eskindeir Ayalew, Terefe Teshome   +3 more
openaire   +1 more source

Pharmacointeraction Network Models Predict Unknown Drug-Drug Interactions [PDF]

, 2013
Drug-drug interactions (DDIs) can lead to serious and potentially lethal adverse events. In recent years, several drugs have been withdrawn from the market due to interaction-related adverse events (AEs).
Arnold, Alana, Cami, Aurel, Manzi, Shannon, Reis, Ben Y.   +3 more
core   +3 more sources

Drug-drug-gene interactions and adverse drug reactions [PDF]

, 2020
The economic and health burden caused by adverse drug reactions has increased dramatically in the last few years. This is likely to be mediated by increasing polypharmacy, which increases the likelihood for drug-drug interactions.
Malki, Mustafa Adnan, Pearson, Ewan Robert   +1 more
core   +2 more sources

Data-driven prediction of adverse drug reactions induced by drug-drug interactions

BMC Pharmacology and Toxicology, 2017
Background The expanded use of multiple drugs has increased the occurrence of adverse drug reactions (ADRs) induced by drug-drug interactions (DDIs). However, such reactions are typically not observed in clinical drug-development studies because most of ...
Ruifeng Liu, Mohamed Diwan M. AbdulHameed, Kamal Kumar, Xueping Yu, Anders Wallqvist, Jaques Reifman   +5 more
doaj   +1 more source

Additional file 1: of Research on the mechanism of drugâ drug interaction between salvianolate injection and aspirin based on the metabolic enzyme and PK-PD model: study protocol for a PK-PD trial

, 2018
SPIRIT 2013 checklist. (DOC 108 kb)
Zhang, Wantong, Zhu, Baochen, Cao, Weiyi, Li, Rui, Wang, Shuge, Gao, Rui   +5 more
openaire   +1 more source

Prevalence of drug-herb and drug-supplement interactions in older adults : A cross-sectional survey [PDF]

, 2018
© British Journal of General PracticeBackground Polypharmacy is common among older adults, with increasing numbers also using prescription drugs with herbal medicinal products (HMPs) and dietary supplements.
Agbabiaka, Alsanad, Arcury, Batanero-Hernán, Blalock, Claire Goodman, Djuv, Farina, Ginter, Gonzàlez-Stuart, Ly, McLay, Neil H Spencer, Peklar, Porqueddu, Qato, Sabina Khanom, Schnabel, Steyn, Taofikat B Agbabiaka   +19 more
core   +2 more sources

Medication Appropriateness, Polypharmacy, and Drug-Drug Interactions in Ambulatory Elderly Patients with Cardiovascular Diseases at Tikur Anbessa Specialized Hospital, Ethiopia

Clinical Interventions in Aging, 2022
Limi Adem, Gobezie T Tegegne Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Science, Addis Ababa University, Addis Ababa, EthiopiaCorrespondence: Gobezie T Tegegne, Email gobezie.temesgen@aau.edu.etBackground ...
Adem L, Tegegne GT
doaj  

Bee Pollen Phytochemicals and Nutrients as Unequaled Pool of Epigenetic Regulators: Implications for Age-Related Diseases

Foods
Bee pollen is characterized by an exceptional diversity and abundance of micronutrients and bioactive phytochemicals. This richness remains very sparsely investigated, but accumulating evidence strongly supports a promising future for bee pollen in human
Rachid Kacemi, Maria G. Campos
doaj   +1 more source

Magnitude of Drug–Drug Interactions in Special Populations

Pharmaceutics, 2022
Drug–drug interactions (DDIs) are one of the most frequent causes of adverse drug reactions or loss of treatment efficacy. The risk of DDIs increases with polypharmacy and is therefore of particular concern in individuals likely to present comorbidities (
Sara Bettonte, Mattia Berton, Catia Marzolini   +2 more
doaj   +1 more source