Results 21 to 30 of about 1,137,228 (316)

The Influence of Pharmacogenetics on the Clinical Relevance of Pharmacokinetic Drug–Drug Interactions: Drug–Gene, Drug–Gene–Gene and Drug–Drug–Gene Interactions

Pharmaceuticals, 2021
Drug interactions are a well-known cause of adverse drug events, and drug interaction databases can help the clinician to recognize and avoid such interactions and their adverse events. However, not every interaction leads to an adverse drug event.
Martina Hahn, Sibylle C. Roll
doaj   +1 more source

Prevalence and Clinical Significance of Drug–Drug and Drug–Dietary Supplement Interactions among Patients Admitted for Cardiothoracic Surgery in Greece

Pharmaceutics, 2021
Background: Drug interactions represent a major issue in clinical settings, especially for critically ill patients such as those with cardiovascular disease (CVD) who require cardiothoracic surgery (CTS) and receive a high number of different medications.
Marios Spanakis, Maria Melissourgaki, George Lazopoulos, Athina E. Patelarou, Evridiki Patelarou   +4 more
doaj   +1 more source

Potential drug interactions : exposure and management in hospital and ambulatory settings [PDF]

, 2006
Health care professionals are responsible to ensure safe dispensing and use of drug regimens involving the use of drug combinations that may interact and cause serious adverse events.
Indermitte, Jörg Lorenz
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Protein-Ligand Interactions and Drug Design

, 2021
This detailed book collects modern and established computer-based methods aimed at addressing the drug discovery challenge from disparate perspectives by exploiting information on ligand-protein recognition.
Ballante, Flavio,
core   +1 more source

Hospital drug safety - role of the pharmacists [PDF]

, 2005
Medication errors and adverse drug reactions are frequent in hospitalized patients. The principle aim of my dissertation was to review the existing data about frequency and risk factors of these findings and to propose measures for their reduction ...
Krähenbühl-Melcher, Anita Maria
core   +1 more source

Potential drug-drug interactions and prescription errors in COVID-19 infected patients

Public Health and Toxicology, 2023
Introduction Prescription errors can cause havoc during the pandemic, especially for comorbid patients with diabetes and hypertension identified as a risky population group for COVID-19.
Syeda R. Tasfia, Hujaifa A. Sakib, Tasmiah Khanam, Nazia Hoque, Mamunur Rahman, Arif Khan, Sufia Islam   +6 more
doaj   +1 more source

Prediction of human drug clearance and anticipation of clinical drug-drug interaction potential from in vitro drug transport studies [PDF]

, 2014
A major concern in drug development is the characterization of new molecular entities (NMEs) with respect to their safety and efficacy. Both factors are determined by the drug’s exposure within the body which itself is affected by drug clearance ...
Kunze, Annett
core   +1 more source

Clinical relevance of drug-drug interactions : a structured assessment procedure. [PDF]

, 2005
Item does not contain fulltextINTRODUCTION: Computerised drug interaction surveillance systems (CIS) may be helpful in detecting clinically significant drug interactions. Experience with CIS reveals that they often yield alerts with questionable clinical
Flikweert, S., Langendijk, PNJ, Smits, P, le Comte, M., Brouwers, J.R.B.J., van Roon, EN; id_orcid, Roon, E.N. van, Langendijk, P.N., Kwee-Zuiderdijk, W.J.M., Brouwers, JRBJ, Flikweert, S, van Roon, E.N., van Roon, EN, Comte, M. le, le Comte, M, Kwee-Zuiderwijk, WJM, Smits, P., Kwee-Zuiderwijk, W.J., Langendijk, P.J.N.   +18 more
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Drug-drug interactions with antiretroviral therapy among people living with HIV in Asia and other regions: Risk factors and impact on indicators of health-related quality of life

Population Medicine, 2022
Introduction While studies have extensively examined the clinical and pharmacokinetic correlates of drug-drug interactions (DDIs) with antiretroviral therapy (ART), less is known about DDIs from the perspective of people living with HIV (PLHIV). Among an
Sejun Park, Yu-Hsiang Hsiao, Fei Yu, Keita Kambara, Brent Allan, Garry Brough, Ta-Fen Hwang, Nathalie Dang, Benjamin Young, Rickesh Patel, Andres Maldonado, Chinyere Okoli   +11 more
doaj   +1 more source

Drug-drug interactions with raltegravir

European Journal of Medical Research, 2009
Objective To review all currently published drug-drug interaction studies with the HIV-integrase inhibitor raltegravir. Methods A PubMed search was conducted for all published reports up to August 1, 2009 as well as a review of updated European and US ...
Burger David M
doaj   +1 more source