Results 31 to 40 of about 1,107,935 (267)
Uncovering New Drug Properties in Target-Based Drug–Drug Similarity Networks [PDF]
, 2020 Despite recent advances in bioinformatics, systems biology, and machine learning, the accurate prediction of drug properties remains an open problem. Indeed, because the biological environment is a complex system, the traditional approach—based on ...
Mihai Udrescu +6 more
core +1 more source
DataSheet1_Opioid Drug-Drug-Drug Interactions and Unintentional Traumatic Injury: Screening to Detect Three-Way Drug Interaction Signals.docx [PDF]
, 2022 Growing evidence suggests that drug interactions may be responsible for much of the known association between opioid use and unintentional traumatic injury.
Sean Hennessy (277760) +10 more
core +1 more source
Drug-drug interactions with raltegravir
European Journal of Medical Research, 2009 Objective To review all currently published drug-drug interaction studies with the HIV-integrase inhibitor raltegravir. Methods A PubMed search was conducted for all published reports up to August 1, 2009 as well as a review of updated European and US ...
Burger David M
doaj +1 more source
BMC Cancer, 2022 Introduction During the cancer treatment path, cancer patients use numerous drugs, including anticancer, supportive, and other prescribed medications, along with herbs and certain products.
Amer A. Koni +8 more
doaj +1 more source
Drug-excipient-shell interactions using thermoplastic starch-based capsules for oral lipid-based drug delivery [PDF]
, 2014 Worldwide, gelatin has been used in the rotary die process as a shell-forming material of soft capsules due to its unique physicochemical properties.
Misic, Zdravka
core +1 more source
PharmaceuticalsClinical practice entails a translation of research that assists in the use of scientific data and therapeutic evidence for the benefit of the patient. This review critically summarizes the potential impact of cannabinoids in conjunction with other drugs
Maria G. Campos +6 more
doaj +1 more source
Evaluation of Pharmacokinetic Drug–Drug Interactions: A Review of the Mechanisms, In Vitro and In Silico Approaches [PDF]
, 2021 Pharmacokinetic drug–drug interactions (DDIs) occur when a drug alters the absorption, transport, distribution, metabolism or excretion of a co-administered agent.
Yaru Peng, Feifan Xie, Zeneng Cheng
core +1 more source
Nature Communications, 2018 SAMHD1 is a critical restriction factor for HIV-1 and its antiviral activity is regulated by T592 phosphorylation. Here, Schott et al. show that the phosphatase PP2A-B55α dephosphorylates SAMHD1 during mitotic exit, rendering it antivirally active in G1 ...
Kerstin Schott +14 more
doaj +1 more source
Insights into CYP2B6-mediated drug–drug interactions
Acta Pharmaceutica Sinica B, 2016 Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. The discovery of multiple important substrates of CYP2B6 as well as polymorphic differences has sparked increasing interest in the ...
William D. Hedrich +2 more
doaj +1 more source
The impact of CYP2C19 genotype on phenoconversion by concomitant medication
Frontiers in Pharmacology, 2023 Introduction: Pharmacogenetics-informed drug prescribing is increasingly applied in clinical practice. Typically, drug metabolizing phenotypes are determined based on genetic test results, whereupon dosage or drugs are adjusted.
Laura M. de Jong +11 more
doaj +1 more source