Results 101 to 110 of about 5,892,906 (287)

Drug-DNA interaction protocols

European Journal of Histochemistry, 2010
In a paper published by Jurgen Drews on the march 17, 2000 issue of Science a figure reporting molecular targets of drug therapy, classified according to biochemical criteria, showed that only 2% of drugs were directed to DNA.
Stefano Govoni
doaj   +1 more source

Clozapine treatment in patients living in the community [PDF]

, 2015
OBJECTIVE: The aim of this study was to assess clozapine treatment in the local community with respect to patient monitoring during dispensing, patient compliance through prescription refills, presence of any other existing co-morbidities and ...
Azzopardi, Lilian M., Schembri, Karl
core  

Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]

, 2003
Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
core   +1 more source

Identification of drug-target interaction by a random walk with restart method on an interactome network

BMC Bioinformatics, 2018
Background Identification of drug-target interactions acts as a key role in drug discovery. However, identifying drug-target interactions via in-vitro, in-vivo experiments are very laborious, time-consuming.
Ingoo Lee, Hojung Nam
doaj   +1 more source

DRUG-DRUG INTERACTION;

The Professional Medical Journal, 2017
Drug-drug interaction (DDI) is a specific type of adverse event, which developsdue to multiple regimen therapy, and that may lead to significant hospitalization and death.Clinical and economic impact of drug interactions are increasingly accredited as a ...
Hina Hasnain, H. Ali, Farya Zafar, Ali Akbar Sial, Kamran Hameed, Huma Shareef, Neelam Mallick, A. Tariq, R. Fatima   +8 more
semanticscholar   +1 more source

Effect of a probiotic mixture on the biotransformation and bioavailability of deglycosylated ginsenosides

Journal of Functional Foods
We aimed to investigate the effects of a probiotic mixture comprising Lactiplantibacillus plantarum, Bifidobacterium breve, Bifidobacterium animal subsp.
So Yeon Jeon, Jihoon Lee, Ji-Hyeon Jeon, Juyoung Kim, Yeon-Ju Baek, Min-Koo Choi, Soohyun Sung, Jong Won Kim, Sanghyun Lim, Im-Sook Song   +9 more
doaj   +1 more source

Randomized pharmacokinetic and drug–drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects

Pharmacology Research & Perspectives, 2015
We assessed pharmacokinetic and safety profiles of ceftazidime–avibactam administered ± metronidazole, and whether drug–drug interactions exist between ceftazidime and avibactam, or ceftazidime‐avibactam and metronidazole.
Shampa Das, Jianguo Li, J. Armstrong, M. Learoyd, T. Edeki   +4 more
semanticscholar   +1 more source

The Effect of Configuration to Interaction Energy Between The Segments of Chitosan and Ascorbic Acid Molecule: Theoretical Study of Drug Release Control [PDF]

, 2015
Polymer systems plays an important role in drug delivery, which can control the time release of the drug, reduce the rate of degradation of the drug, and can reduce the toxic properties of the drug.
Hildayani, Suci Zulaikha, Siahaan, Parsaoran   +1 more
core  

Psychotropic Drugs (2) Interaction between Monoamine Oxidase (MAO) Inhibitors and other Substances [PDF]

, 1965
Folke Sjöqvist
openalex   +1 more source

Elucidating Signal Transduction Modulatory Drug Target Network of Colon Cancer: A Network Biology Approach [PDF]

, 2010
Latest evaluation and validation of cancer drugs and their targets has demonstrated the lack and inadequate development of new and better drugs, based on available protocols.
Biplab Bhattacharjee, Deepak Ranjan Sethi, Ibnul Hassan, Jayadeepa R.M, Sanjay Kundu, Sushil Kumar Middha   +5 more
core   +1 more source