Results 101 to 110 of about 2,202,582 (329)
An Ontology for formal representation of Drug Drug Interaction Knowledge [PDF]
, 2013 The poster at: The Sixth International Biocuration Conference (Biocuration 2013), took at April 7–10, 2013 in Churchill College, Cambridge, UK. The event web site in: http://www.ebi.ac.uk/biocuration2013/content/homeOntologies are useful tools in ...
Herrero Zazo, María +2 more
core +1 more source
Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters [PDF]
, 2019 OBJECTIVES: The secondary use of medical data contained in electronic medical records, such as hospital discharge letters, is a valuable resource for the improvement of clinical care (e.g. in terms of medication safety) or for research purposes. However,
Demuth, Ilja +4 more
core +1 more source
519. DeepLPI: A Novel Drug Repurposing Model based on Ligand-Protein Interaction Using Deep Learning [PDF]
, 2022 Bomin Wei, Yue Zhang, Xiang Gong
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Mechanisms and the clinical relevance of complex drug–drug interactions
Clinical Pharmacology: Advances and Applications, 2018 Arthur G Roberts, Morgan E Gibbs Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA, USA Abstract: As a result of an increasing aging population, the number of individuals taking multiple medications simultaneously has grown ...
Roberts AG, Gibbs ME
doaj
Drug-DNA interaction protocols
European Journal of Histochemistry, 2010 In a paper published by Jurgen Drews on the march 17, 2000 issue of Science a figure reporting molecular targets of drug therapy, classified according to biochemical criteria, showed that only 2% of drugs were directed to DNA.
Stefano Govoni
doaj +1 more source
Drug–drug interactions with imatinib
Medicine, 2016 Many patients treated with imatinib, used in cancer treatment, are using several other drugs that could interact with imatinib. Our aim was to study all the drug-drug interactions (DDIs) observed in patients treated with imatinib.We performed 2 observational studies, between the 1st January 2012 and the 31st August 2015 in the Midi-Pyrénées area (South
Récoché, Isabelle +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Journal of Functional FoodsWe aimed to investigate the effects of a probiotic mixture comprising Lactiplantibacillus plantarum, Bifidobacterium breve, Bifidobacterium animal subsp.
So Yeon Jeon +9 more
doaj +1 more source
BMC Bioinformatics, 2018 Background Identification of drug-target interactions acts as a key role in drug discovery. However, identifying drug-target interactions via in-vitro, in-vivo experiments are very laborious, time-consuming.
Ingoo Lee, Hojung Nam
doaj +1 more source