Results 211 to 220 of about 2,242,237 (349)

Enhanced CYP2C19-mediated drug-drug interaction risk with escitalopram in geriatric populations. [PDF]

Front Pharmacol
Byoun S, Heo DG, Lee M, Lee R, Li Y, Lee JY, Hong E, Lee W.   +7 more
europepmc   +1 more source

Additional file 2 of DLDTI: a learning-based framework for drug-target interaction identification using neural networks and network representation

, 2020
Yihan Zhao, Kai Zheng, Baoyi Guan, Mengmeng Guo, Lei Song, Jie Gao, Hua Qu, Yuhui Wang, Dazhuo Shi, Ying Zhang   +9 more
openalex   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Drug-Drug Interaction Liabilities with BTK Inhibitor TL-895. [PDF]

Cancer Res Commun
Stromatt JC, Ahmed EA, Drabison T, Nepal MR, Chowdhury AT, Orwick SJ, Buelow DR, Eisenmann ED, Huang KM, Sparreboom A, Baker SD.   +10 more
europepmc   +1 more source

Pharmacoepidemiology and Drug-Drug interactions in various regions of Andhra Pradesh

, 2021
M Bothiraj, M Alagusundaram, Chandra Sekhar K B   +2 more
openalex   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Polypharmacy and Drug-Drug Interaction Architecture in Hospitalized Cardiovascular Patients: Insights from Real-World Analysis. [PDF]

Biomedicines
Radu AF, Radu A, Bungau GS, Tit DM, Vesa CM, Jurca T, Uivarosan D, Gitea D, Brata R, Bustea C.   +9 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Machine learning models for drug-drug interaction prediction from computational discovery to clinical application. [PDF]

NPJ Digit Med
Lu Y, Chen J, Fan N, Song W, Sheng H, Yang Y, Wang J.   +6 more
europepmc   +1 more source

Computational and umbrella sampling analysis of HER2 D769H and D769Y variants: mutation-specific structural alterations and drug interactions in breast cancer

Tamizhini Loganathan, G. Priya Doss
openalex   +2 more sources