Results 221 to 230 of about 6,006,054 (377)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

UGT2B7-mediated drug-drug interaction between cannabinoids and hydromorphone. [PDF]

Drug Metab Dispos
Coates S, Bardhi K, Zhao M, Lazarus P.
europepmc   +1 more source

Microstructural-Mechanical Interactions of Drug Coated Balloons

, 2019
Jesse Lauber, John M. Warrington, Christopher L. Wu, Justin Gerow   +3 more
openalex   +2 more sources

Possible Drug-Drug Interactions of Hydroxychloroquine with Concomitant Medications in Prophylaxis and Treatment of COVID-19: Multiple Standard Software Based Assessment

, 2020
P Ansumsn Abhisek, Shweta Supriya Pradhan   +1 more
openalex   +1 more source

Biochemical Evaluation of Combination Drug Interaction Between Phenobarbitone and Halofantrine in Weaning Rats [PDF]

, 2003
H.C.C. Maduka, Aliyu Salihu, Viola A. Onwuliri   +2 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A Dose-Aware Model for Revealing Dose-Risk Relationship of Drug-Drug Interaction. [PDF]

CPT Pharmacometrics Syst Pharmacol
Shi Y, Sun A, Yang Y, Nan H, Xu J, Shan M, Eadon MT, Su J, Zhang P.   +8 more
europepmc   +1 more source

Impact of posaconazole tablets for secondary prophylaxis on drug interactions in haploidentical allogeneic stem cell transplantation: A single-arm, open-label, prospective study

Xiaoning Wang, Yuqi Wang, Pengcheng He
openalex   +1 more source

Drug-drug interaction between TAS-303 and simvastatin/midazolam in healthy subjects

, 2018
Yuji Kumagai, Tomoe Fujita, Masako Aso, Hideki Amano, Yoshinobu Sasaki, Masaki Kawai, Toru Takenaka, Makoto Nagaoka, Koichiro Hoashi   +8 more
openalex   +2 more sources

P171 Drug-drug interactions in hiv patients taking pharmacokinetic enhancers [PDF]

, 2017
Rachel MacCann, Paul Hollywood, Samuel McConkey, David Lorigan   +3 more
openalex   +1 more source