Results 251 to 260 of about 6,006,054 (377)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Association Study of OATP1B3 Polymorphisms on Hepatic Uptake and Drug-Drug Interaction <i>In Vitro</i>. [PDF]

ACS Omega
Yang Z, Chen Y, Tian G, Wang X, Wang Z.
europepmc   +1 more source

Drug interaction (17. combination with hyperlipidemia) [PDF]

, 2010
Kawasaki, Yoichi, Matsunaga, Hisashi, Sendo, Toshiaki   +2 more
core   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Antiestrogenic drugs and atracurium - a possible interaction? [PDF]

, 1986
Mohamed Naguib, Henry K. Gyasi
openalex   +1 more source

A probabilistic approach for collective similarity-based drug-drug interaction prediction

Bioinform., 2016
Dhanya Sridhar, Shobeir Fakhraei, L. Getoor   +2 more
semanticscholar   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Effect of electronic drug-drug interaction alerts on patient and clinician outcomes: a systematic review. [PDF]

J Am Med Inform Assoc
Holbrook AM, Silva JM, Faruque JAY, Deng J, Schneider T, Jaffer A.   +5 more
europepmc   +1 more source

Recommendations to improve the usability of drug-drug interaction clinical decision support alerts

J. Am. Medical Informatics Assoc., 2015
T. Payne, L. Hines, Raymond C. Chan, Seth Hartman, J. Kapusnik-Uner, Alissa L. Russ, B. Chaffee, Christian Hartman, Victoria Tamis, Brian Galbreth, P. Glassman, S. Phansalkar, H. Sijs, S. Gephart, G. Mann, H. Strasberg, A. Grizzle, Mary Brown, G. Kuperman, C. Steiner, Amanda Sullins, Hugh Ryan, Michael A. Wittie, D. Malone   +23 more
semanticscholar   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source