Results 51 to 60 of about 2,202,582 (329)
Trends of Analytical Research on Drug-drug Interaction [PDF]
, 2014 薬物-薬物相互作用は薬物治療において非常に重要な事項である｡薬物はそれ自身で副作用を生じうるが､複数の薬物を併用することで予期しない重篤な有害事象を引き起こすこともある｡この意味で､薬物-薬物相互作用に関する分析化学的な研究が非常に重要であり､薬物治療の手助けとなる｡本総説では､薬物-薬物相互作用の分析化学的研究の最近の動向について､特に微小透析技術に基づいた方法について記述する｡Drug-drug interaction is very important matter for the ...
Kenichiro NAKASHIMA +7 more
core +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, EarlyView.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Viruses, 2015 With the goal of recognizing outstanding contributions to the field of virology by early-career investigators, last year Viruses accepted nominations for a 2015 Young Investigator Prize in Virology. The target age was set at 40 and under.
Eric O. Freed
doaj +1 more source
Pharmaceutics, 2021 An active wound dressing should address the main goals in wound treatment, which are improved wound healing and reduced infection rates. We developed novel multifunctional nanofibrous wound dressings with three active ingredients: chloramphenicol (CAM ...
Laura Victoria Schulte-Werning +6 more
doaj +1 more source
Potensi Interaksi Obat Pada Pasien Gangguan Ginjal Kronis di Instalasi Rawat Inap RSUD Dr. Moewardi Tahun 2014 [PDF]
, 2016 Chronic kidney disease (CKD) is a condition which characterized by a gradual loss of kidney function accompanied by manifestations of kidney pathology abnormality for at least three months. Patients with chronic kidney disease who have some complications
Khasanah, Rizqi Nurul
core
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Detecting drug interactions using personal digital assistants in an out-patient clinic [PDF]
, 2017 Background: The installation of drug databases on personal digital assistants (PDAs) allows for rapid detection of adverse drug interactions at the point of care.
Bovier, P.A. +2 more
core
Systematic Exploration of Synergistic Drug Pairs [PDF]
, 2013 Drug synergy allows a therapeutic effect to be achieved with lower doses of component drugs. Drug synergy can result when drugs target the products of genes that act in parallel pathways (‘specific synergy’).
Andrews, Brenda J +14 more
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source