Results 161 to 170 of about 1,413,692 (298)
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Recurrent Drug-Induced Pneumothorax Associated With Lenvatinib: A Case Report. [PDF]
Torii R+5 more
europepmc +1 more source
Effects of Some Ions and Drugs on the Aconitine-induced Fibrillation of the Purkinje Fibers
Issei Imanaga
openalex +2 more sources
Drug-induced agranulocytosis: in vitro evidence for immune suppression of granulopoiesis and a cross-reacting lymphocyte antibody [PDF]
R Taetle, TA Lane, J Mendelsohn
openalex +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
Natural History of Idiosyncratic Drug-Induced Liver Injury and Prognostic Models. [PDF]
Devarbhavi HC, Andrade RJ.
europepmc +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou+5 more
wiley +1 more source
Towards standardized skin testing for drug-induced allergic reactions. [PDF]
AlGassim M+11 more
europepmc +1 more source
Drug‐induced changes in the release of [3H]‐noradrenaline from field stimulated rat iris [PDF]
L.‐O. Farnebo, Bertil Hamberger
openalex +1 more source