Results 41 to 50 of about 390,946 (318)

Study of Cytogenetic Effects of Cimetidine Drug in White mice (Mus musculus) [PDF]

Engineering and Technology Journal, 2017
This study aimed to detect the cytogenetic effects of Cimetidine drug, which used in the treatment of gastric ulceration, reflux oesophagitis through the tests (mitotic index of Somatic cells in bone marrow and spleen, frequency of micronuclei ...
T.G. Mohamed, A.A. Mohamed
doaj   +1 more source

Maladaptive plasticity in levodopa-induced dyskinesias and tardive dyskinesias: old and new insights on the effects of dopamine receptor pharmacology. [PDF]

, 2014
Maladaptive plasticity can be defined as behavioral loss or even development of disease symptoms resulting from aberrant plasticity changes in the human brain.
Ahmed, Ananth, Aron, Aron, Baldessarini, Breakefield, Brooks, Byl, Calabresi, Calabresi, Carta, Casey, Casey, Castrén, Cenci, Cenci, Cerasa, Cerasa, Cerasa, Cerasa, Cerasa, Clarke, Crow, Crow, de la Fuente-Fernandez, de la Fuente-Fernandez, Fahn, Ganos, Gottwald, Heckers, Jankovic, Jellinger, Jenner, Kishore, Kishore, Koch, Koch, Koch, Li, Marsden, McEwen, Morgante, Nambu, Obeso, Pakkenberg, Peralta, Picconi, Quartarone, Rascol, Rylander, Salgado-Pineda, Sawada, Sgambato-Faure, Sigwald, Spencer, Teo, Vernon, Vernon, Zesiewicz   +58 more
core   +2 more sources

Giant right coronary artery aneurysm. Case Report

Case Reports, 2020
Introduction: Coronary aneurysms are rare and are linked to drug abuse; symptomatology depends on the coronary anatomy. This is a case of acute coronary syndrome associated with a giant right coronary aneurysm.
Benjamín Iván Hernández-Mejía, Edison Ricardo Espinoza-Saquicela   +1 more
doaj   +1 more source

Indigenous Herbal Drug (Tinospora Cordifolia) Induced Liver Injury: A Case Report [PDF]

Bengal Physician Journal
Drug-induced liver injury (DILI) is a condition characterized by acute or chronic liver damage following the use of hepatotoxic drugs. It can be classified based on clinical presentation (hepatocellular, cholestasis, or mixed), mechanism of ...
Sounak Kumar Roy, Muniruddin SK, Subham Mondal, Sandipan Mukherjee, Santa Subhra Chatterjee   +4 more
doaj   +1 more source

The side effects (cytogenetics ) of Methotrexate drug on male germ cells of Mus musculus

مجلة مركز بحوث التقنيات الاحيائية, 2011
In this study three doses (0.01, 0.02, 0.04) mgkg B.W of methotrexate drug which used, in the treatment of bladder cancer, were investigate in male germ cells of Mus musculus.
Abbas A. Mohammed, Ali A. Al-Temimi, Ahmed Abdul Amier Hussain Al-Amiery   +2 more
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Modeling neurocognitive and neurobiological recovery in addiction [PDF]

, 2019
This book focuses on "what to know" and "how to apply" information, prioritizing novel principles and delineating cutting-edge assessment, phenotyping and treatment ...
Abé, Agartz, Aharonovich, Almeida, Anderson, Bae, Bates, Bernardin, Blaine, Block, Bolla, Brody, Buhler, Cardenas, Cardenas, Cavazos-Rehg, Chang, Chang, Charlet, Crews, Crews, de Wit, Demirakca, Di Sclafani, Dlugos, Dom, Dominguez-Salas, Duka, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Eldreth, Ernst, Ernst, Ernst, Ersche, Ersche, Fein, Fein, Fein, Fernandez-Serrano, Fernandez-Serrano, Franklin, Gansler, Gazdzinski, Gazdzinski, Gazdzinski, Gazdzinski, Giorgi, Glass, Goldstein, Goldstein, Hanlon, Hasin, Heinz, Hermann, Hirsiger, Hoefer, Holman, Humphreys, Hwang, Iudicello, Kalman, Ke, Kim, Klein, Koob, Le Berre, Licata, Loeber, Mackey, Matochik, Matochik, Medina, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Mon, Mon, Mon, Moorman, Morales, Moreno-Alcázar, Moss, Murray, Murray, Nader, Nicolas, Nordahl, Noyan, O'Neill, Oishi, Oscar-Berman, Oscar-Berman, Parks, Parvaz, Passetti, Pennington, Pennington, Pfefferbaum, Prescot, Prescot, Rabin, Rando, Rezapour, Rogers, Rourke, Rupp, Sailasuta, Salo, Schmidt, Schulte, Segobin, Seo, Seo, Simon, Sneider, Sorg, Stavro, Stevens, Streeter, Sullivan, Sullivan, Sullivan, Sullivan, Thompson, Tunving, van Eijk, Verdejo-Garcia, Verdejo-Garcia, Verdejo-Garcia, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Vonmoos, Walitzer, Wang, Wang, Wang, Weber, Weinberger, Weinberger, Weinberger, Williams, Witkiewitz, Xiao, Yang, Yeh, Yoon, Younger, Yucel, Zahr, Zahr, Zatorre, Zou   +179 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]

, 2014
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora, Barreiro, Eshter, Chacon Cabrera, Alba, Diament, Miriam, Fermoselle, Clara, Mateu Jimenez, Mercè, Sandri, Marco, Urtreger, Alejandro Jorge   +7 more
core   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source