Results 51 to 60 of about 390,946 (318)

Atrial Fibrillation Associated with Anticancer Drugs

Безопасность и риск фармакотерапии, 2020
Atrial fibrillation is a serious adverse reaction associated with the use of anticancer drugs. The aim of the study was to analyse scientific literature on the prevalence, pathophysiological mechanisms, and risk factors of anticancer drug-induced atrial ...
O. D. Ostroumova, M. S. Chernyaeva, A. I. Kochetkov, D. I. Bakhteeva, S. N. Ivanov, D. A. Sychev   +5 more
doaj   +1 more source

Smoke, alcohol and drug addiction and male fertility [PDF]

, 2018
In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates and costs.
DE ANGELIS, Cristina Concetta, Di Dato, Carla, Gianfrilli, Daniele, Isidori, Andrea, Menafra, Davide, Pivonello, Rosario, Pozza, Carlotta, Sansone, Andrea   +7 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Pancreatitis following Olanzapine Therapy: A Report of Three Cases [PDF]

, 2007
CONTEXT: Atypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. CASE REPORT: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being ...
Azar, Riad, Jonnalagadda, Sreenivasa, Kerr, Thomas A., Prakash, Chandra   +3 more
core   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Methotrexate hepatotoxicity in patients with rheumatoid arthritis. [PDF]

, 2010
BACKGROUND Increases in aminotransferases (transaminitis) are potential major adverse reactions seen with long-term use of methotrexate (MTX). The aim of this study, therefore was to evaluate the incidence of MTX induced hepatotoxicity and its risk ...
Akhlaghi, M, Anvari, B, Kolahdoozan, S, Shahraeeni, S, Sotoudehmanesh, R   +4 more
core  

Abnormal hippocampal melatoninergic system: a potential link between absence epilepsy and depression-like behavior in WAG/Rij rats? [PDF]

, 2018
Absence epilepsy and depression are comorbid disorders, but the molecular link between the two disorders is unknown. Here, we examined the role of the melatoninergic system in the pathophysiology of spike and wave discharges (SWDs) and depression-like ...
Battaglia, Giuseppe, Bucci, Domenico, Celli, Roberta, De Fusco, Antonio, Mastroiacovo, Federica, Moyanova, Slavianka, Nicoletti, Ferdinando, Santolini, Ines, Tchekalarova, Jane   +8 more
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Obstrução intestinal após uso de infliximab no tratamento de fístula êntero-cutânea na doença de Crohn

Revista do Colégio Brasileiro de Cirurgiões
Crohn's disease is often complicated by the development of fistulas. Infliximab, a monoclonal antibody that binds tumor necrosis factor a have shown to be successful in the treatment of fistulizing Crohn's disease.
Carolina Gomes Gonçalves, Júlio Cezar Uili Coelho, Heda Maria Braska dos Santos Amarante   +2 more
doaj   +1 more source

Lamotrigine hypersensitivity syndrome and spiking fever

Indian Journal of Dermatology, 2012
We report a case of a 26 year old woman with rash, lymphadenopathy, liver enzyme abnormalities and spiking fever. She was diagnosed with drug-induced hypersensitivity syndrome (DHS) to lamotrigine.
Christiaan V Bakker, Vincent Noordhoek Hegt, Marinus C G Van Praag   +2 more
doaj   +1 more source