Propagation of Pericentral Necrosis During Acetaminophen-Induced Liver Injury: Evidence for Early Interhepatocyte Communication and Information Exchange. [PDF]
, 2019 Acetaminophen (APAP)-induced liver injury is clinically significant, and APAP overdose in mice often serves as a model for drug-induced liver injury in humans.
Hunt, C Anthony +5 more
core
A Complex Case of Cholestasis in a Patient with ABCB4 and ABCB11 Mutations [PDF]
, 2018 The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a form of symptomatic cholelithiasis occurring in young adults, characterized by recurrence of symptoms after cholecystectomy and presence of hepatolithiasis.
Anapaz, V +7 more
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
CD36 deficiency ameliorates drug-induced acute liver injury in mice [PDF]
, 2021 Chen Zhang +12 more
openalex +1 more source
Chip-based liver equivalents for toxicity testing - organotypicalness versus cost-efficient high throughput [PDF]
, 2013 Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Marx, Uwe +2 more
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Advanced Engineering Materials, EarlyView.Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello +5 more
wiley +1 more source
Ginseng-Related Drug-Induced Liver Injury
Case Reports in Gastroenterology, 2018 Ginseng is commonly used as a medicinal herb for memory and concentration and general well-being. Drug-induced liver injury (DILI) is one of the most challenging disorders and trending events in the United States which are related to body building and ...
Kyawzaw Lin +5 more
doaj +1 more source
Drug-induced liver injury following the use of tocilizumab or sarilumab in patients with coronavirus disease 2019 [PDF]
, 2022 Qian Gao +7 more
openalex +1 more source
The Hepatocellular Hypoxia Criteria:2’Nitroimidazole Effect on Hepatocyte Carbohydrate Metabolizing Enzymes [PDF]
, 2008 Aim: to understand the 2’-nitroimidazole induced hypoxia and liver cell interaction, we proposed a “Hapatocellular Hypoxia Criteria”.
Rakesh Sharma
core +1 more source