Results 151 to 160 of about 400,521 (193)

ATG16L1 Regulates Reparative Function of Peritoneal Macrophages During Acute Drug-induced Liver Injury. [PDF]

open access: yesCell Mol Gastroenterol Hepatol
Wang X   +7 more
europepmc   +1 more source

Drug-induced liver injury prediction based on graph convolutional networks and toxicogenomics. [PDF]

open access: yesPLoS Comput Biol
Xiao T   +10 more
europepmc   +1 more source

Drug-Induced Liver Injury

Critical Care Nursing Clinics of North America, 2022
Drug-induced liver injury (DILI) is a spectrum of liver injuries that can be classified by phenotype and injury patterns. Some injury patterns can be predicted in a number of drugs that are commonly used in practice, but idiosyncratic reactions are unpredictable and are not dose related.
Edmond Atallah, Guruprasad P. Aithal
  +5 more sources

Drug-induced liver injury

Current Opinion in Gastroenterology, 2012
Drug-induced liver injury (DILI) remains an important disease in clinical practice. It is difficult to predict, diagnose and manage. Studies in the peer-reviewed literature in the last 2 years, focusing on the diagnosis, prediction and management of DILI will be reviewed.Antibiotics remain the most common drug causing DILI in the United States and ...
Lafaine M, Grant, Don C, Rockey
  +5 more sources

Drug-Induced Liver Injury

The Journal for Nurse Practitioners, 2009
Many drugs and environmental chemicals are capable of evoking some degree of liver injury. The liver represents a primary target for adverse drug reactions due to its central role in biotransformation and excretion of foreign compounds, its portal location within the circulation exposing it to a wide variety of substances, and its anatomic and ...
Michael, Holt, Cynthia, Ju
openaire   +3 more sources

Drug-Induced Liver Injury

Hospital Practice, 1978
In the usual course of events, the liver detoxifies hepatocytotoxic intermediates of drug metabolism. But when protective systems are overloaded by normally harmless drugs, the intermediates can cause massive, even fatal, hepatic necrosis.
J R, Mitchell, B H, Lauterburg
openaire   +2 more sources

Drug-Induced Liver Injury

Veterinary Clinics of North America: Small Animal Practice
Drug-induced liver injury (DILI) is an underrecognized cause of hepatic disease in dogs and cats. Successful identification of cases requires an initial suspicion by the practitioner, a thorough drug exposure history, and knowledge of the toxic potential for common veterinary drugs.
Mariana Mesquita   +2 more
  +5 more sources

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