Results 161 to 170 of about 400,521 (193)
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Drug‐Induced Liver Injury After Liver Transplantation
Liver Transplantation, 2020Drug‐induced liver injury (DILI) is an adverse reaction to many drugs in common use that in a liver transplantation (LT) recipient may cause graft dysfunction and may even lead to graft loss and the need for retransplantation. However, several potential clinical scenarios, such as graft rejection and infection, can confound the diagnosis of suspected ...
Miguel, Jiménez-Pérez +3 more
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Drug Safety, 2007
Drug-induced liver injury is a frequent cause of hepatic dysfunction. Reliably establishing whether the liver disease was caused by a drug requires the exclusion of other plausible causes and the search for a clinical drug signature. The drug signature consists of the pattern of liver test abnormality, the duration of latency to symptomatic ...
Gebran, Abboud, Neil, Kaplowitz
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Drug-induced liver injury is a frequent cause of hepatic dysfunction. Reliably establishing whether the liver disease was caused by a drug requires the exclusion of other plausible causes and the search for a clinical drug signature. The drug signature consists of the pattern of liver test abnormality, the duration of latency to symptomatic ...
Gebran, Abboud, Neil, Kaplowitz
openaire +2 more sources
Drug-Induced Hepatotoxicity or Drug-Induced Liver Injury
Clinics in Liver Disease, 2009Drug-induced hepatotoxicity is underreported and underestimated in the United States. It is an important cause of acute liver failure. Common classes of drugs causing drug-induced hepatotoxicity include antibiotics, lipid lowering agents, oral hypoglycemics, psychotropics, antiretrovirals, acetaminophen, and complementary and alternative medications ...
Aaron J, Pugh +4 more
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Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006
Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal. It is important to recognize and remove the offending agent as quickly as possible to prevent the progression to chronic liver disease and/or acute liver failure.
Herbert L. Bonkovsky +3 more
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Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal. It is important to recognize and remove the offending agent as quickly as possible to prevent the progression to chronic liver disease and/or acute liver failure.
Herbert L. Bonkovsky +3 more
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Medicine, 2011
Abstract Drug-induced liver injury (DILI) accounts for 9.5% of all suspected adverse drug reactions (ADRs) and for a significant proportion of fatal ADRs. DILI may be a direct toxic effect or an immunological reaction to either the drug or an active metabolite. Drugs can cause a diverse array of liver injury, which may be acute or chronic.
Adam D. Farmer, Alison Brind
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Abstract Drug-induced liver injury (DILI) accounts for 9.5% of all suspected adverse drug reactions (ADRs) and for a significant proportion of fatal ADRs. DILI may be a direct toxic effect or an immunological reaction to either the drug or an active metabolite. Drugs can cause a diverse array of liver injury, which may be acute or chronic.
Adam D. Farmer, Alison Brind
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1987
The manifold aspects of adverse hepatic drug reactions which have been frequently reviewed (Kaplowitz et al. 1986; Ludwig and Axelsen 1983; Popper et al. 1972; Strieker and Spoelstra 1985; Zimmerman 1978) include (a) pharmacology, based also on the chemical constitution of the drug, (b) mechanistics, dealing with the pathogenesis of the reaction, (c ...
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The manifold aspects of adverse hepatic drug reactions which have been frequently reviewed (Kaplowitz et al. 1986; Ludwig and Axelsen 1983; Popper et al. 1972; Strieker and Spoelstra 1985; Zimmerman 1978) include (a) pharmacology, based also on the chemical constitution of the drug, (b) mechanistics, dealing with the pathogenesis of the reaction, (c ...
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2018
Drug-induced liver injury (DILI) accounts for about 50% of acute liver failure cases in the United States. Diagnosis is challenging, especially due to the myriad combinations of potentially hepatotoxic medications and clinical presentations. Unexplained liver injury should prompt a thorough investigation of medication administration (e.g., for ...
Dennis L. Shung, Joseph K. Lim
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Drug-induced liver injury (DILI) accounts for about 50% of acute liver failure cases in the United States. Diagnosis is challenging, especially due to the myriad combinations of potentially hepatotoxic medications and clinical presentations. Unexplained liver injury should prompt a thorough investigation of medication administration (e.g., for ...
Dennis L. Shung, Joseph K. Lim
openaire +1 more source
Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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The gut–liver axis and gut microbiota in health and liver disease
Nature Reviews Microbiology, 2023Cynthia Li-Shin Hsu, Bernd Schnabl
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Disparities in liver cancer occurrence in the United States by race/ethnicity and state
Ca-A Cancer Journal for Clinicians, 2017Farhad Islami +2 more
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