Results 81 to 90 of about 524,198 (385)
Relationship Between Characteristics of Medications and Drug-Induced Liver Disease Phenotype and Outcome [PDF]
, 2014 Background & Aims: It is not known if specific characteristics of medication are associated with type of drug-induced liver injury (DILI) or outcome.
Chalasani, Naga +8 more
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects
Oxidative Medicine and Cellular Longevity, 2021 Oxidative stress is a key pathological feature implicated in both acute and chronic liver diseases, including drug-induced liver injury (DILI).
Yonela Ntamo +9 more
semanticscholar +1 more source
Hepatitis E Virus Detection in Liver Tissue from Patients with Suspected Drug-Induced Liver Injury [PDF]
, 2015 Hepatitis E virus (HEV) infection is increasingly recognized as a cause of acute hepatitis in the industrialized world. We aimed to determine the frequency of acute Hepatitis E virus (HEV) infection in cases of suspected drug-induced liver injury (DILI),
Achim Weber +3 more
core +2 more sources
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Chinese MedicineBackground Prediabetes mellitus (PreDM) is a high-risk state for developing type 2 diabetes mellitus (T2DM) and often goes undiagnosed, which is closely associated with obesity and characterized by insulin resistance that urgently needs to be treated ...
Qin Lan +7 more
doaj +1 more source
Immune-Mediated Drug-Induced Liver Injury: Immunogenetics and Experimental Models
International Journal of Molecular Sciences, 2021 Drug-induced liver injury (DILI) is a challenging clinical event in medicine, particularly because of its ability to present with a variety of phenotypes including that of autoimmune hepatitis or other immune mediated liver injuries.
A. Gerussi +8 more
semanticscholar +1 more source
Attenuation of ischemic liver injury by prostaglandin E
, 1998 Background: Prostaglandin has been reported to have protective effects against liver injury. Use of this agent in clinical settings, however, is limited because of drugrelated side effects.
Ishizaki, N +8 more
core +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Drug-Induced Liver Injury in COVID-19 Patients: A Systematic Review
Frontiers in Medicine, 2021 Introduction: The severity of COVID-19 may be correlated with the risk of liver injury development. An increasing number of studies indicate that degrees of hepatotoxicity has been associated with using some medications in the management of COVID-19 ...
F. Sodeifian +7 more
semanticscholar +1 more source