Results 41 to 50 of about 15,916,923 (300)
AN INVESTIGATION INTO THE VALUE OF A STANDARDISED GLOBAL PHARMACOVIGILANCE REPORTING SYSTEM
Pharmacovigilance (PV) is based on the medical assessment of adverse medical events or drug-related problems, collected within organised health programmes.
Schurer, Maximillian Juan +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Background: Drug-related problems (DRPs) potentially contribute to morbidity, mortality and financial indicators. There is increasing evidence that participation and interventions of clinical pharmacists in health care have a positive influence on ...
Aziz Ullah Khan +3 more
doaj +1 more source
Overview of drug-related problems (DRPs) at hospitalization, identified by clinical pharmacists, in patients with drug-related hospitalization (DRH) versus non-drug-related hospitalizations (non-DRHs) in the study population (n = 395a).
Kristin Kvernrød (7022792) +5 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Drug related problems in older adults living with dementia.
BackgroundCompared with those without dementia, older patients with dementia admitted to acute care settings are at higher risk for triad combination of polypharmacy (PP), potentially inappropriate medication (PIM), and drug-drug interaction (DDI), which
Sirasa Ruangritchankul +3 more
doaj +1 more source
Drug-Related Problems in Pulmonary Hypertension with Valvular Heart Disease
Farizan Abdul-Ghaffar,1,2 Adyani Md Redzuan,1 Mohd Makmor-Bakry,1 Mohamad Arif Muhamad Nor3 1Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; 2Department of Pharmacy, Hospital Serdang, Kajang, Malaysia; 3Department of ...
Md Redzuan A +3 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Drug-related problems (DRPs) identified from geriatric medication safety review clinics
Drug-related problems (DRPs) were identified from baseline data of 193 Medication Safety Review Clinic (MSRC) patients. MSRCs enroll older adults (>= 65 years) with either (1) prescriptions of >= 8 chronic medications (drugs prescribed for >= 28
Chan, Ding-Cheng;Chen, Jen-Hau;Kuo, Hsu-Ko;We, Chiung-Jung;Lu, I-Shu;Chiu, Lee-Shu;Wu, Shwu-Chong +1 more
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

