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Supports needed for Irish families mourning drug-related deaths.
, 2022 Opinion: families who lose a loved one to a drug death experience a silent grief that puts them at risk of intense mental and physical health problems..
O'Callaghan, Daniel, Lambert, Sharon
core
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Drug-Related Problems in HIV Treatment Failure. [PDF]
CureusBackground Antiretroviral therapy (ART) is used in human immunodeficiency virus (HIV) treatment to reduce morbidity and mortality rates among people living with the virus. The types of drug-related problems (DRPs) and their causes that contributed to HIV treatment failure were unknown.
Che Pa MF +4 more
europepmc +3 more sources
Archives of EpilepsyObjective: Interventions by clinical pharmacists are required to identify and resolve medication-related problems. This study aimed to identify drug-related problems (DRPs) encountered by patients with epilepsy, provide pharmaceutical care (PC ...
Unyime Eshiet +2 more
doaj +1 more source
Negative Outcomes Associated with Medication in Neonates on Parenteral Nutrition Therapy
Pediatric Reports, 2023 Objective: In Ecuador, studies on clinical daily practice problems focused on parenteral nutrition in neonates are scarce. Therefore, this research aimed to identify negative results associated with medications (NRAM) in neonates with parenteral ...
Evelin Nataly Vega Díaz +4 more
doaj +1 more source
Alcohol‐ and drug‐related absenteeism: a costly problem
Australian and New Zealand Journal of Public Health, 2016 Absenteeism related to alcohol and other drug (AOD) use can place a substantial burden on businesses and society. This study estimated the cost of AOD-related absenteeism in Australia using a nationally representative dataset.A secondary analysis of the 2013 National Drug Strategy Household Survey (n=12,196) was undertaken.
Ann Roche, Ken Pidd, Victoria Kostadinov
openaire +3 more sources
Acute health problems due to recreational drug use in patients presenting to an urban emergency department in Switzerland [PDF]
, 2015 QUESTIONS UNDER STUDY: To describe acute toxicity of recreational drugs including novel psychoactive substances. METHODS: We included all cases presenting at the emergency department (ED) of the University Hospital of Basel, Switzerland, between ...
Dolder, Patrick C. +13 more
core +2 more sources
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Pharmacist interventions for older adults with polypharmacy in an ambulatory geriatric clinic
Health Literacy and Communication OpenIntroduction Polypharmacy is a concern among older adults. An academic medical center in northeast Ohio currently has an outpatient geriatric medicine clinic with an embedded board-certified geriatric pharmacist who performs comprehensive medication ...
Antonietta Paneccasio +6 more
doaj +1 more source