Impact of polymorphisms in transporter and metabolizing enzyme genes on olanzapine pharmacokinetics and safety in healthy volunteers [PDF]
, 2020 Olanzapine is an atypical antipsychotic widely used for the treatment of schizophrenia, which often causes serious adverse drug reactions. Currently, there are no clinical guidelines implementing pharmacogenetic information on olanzapine.
Abad-Santos, Francisco +11 more
core +1 more source
WITHDRAWN-a resource for withdrawn and discontinued drugs [PDF]
, 2015 Post-marketing drug withdrawals can be associated with various events, ranging from safety issues such as reported deaths or severe side-effects, to a multitude of non-safety problems including lack of efficacy, manufacturing, regulatory or business ...
Drwal, M.N. +5 more
core +3 more sources
Adverse drug reactions reported over 5 years in a regional university hospital [PDF]
Journal of Medicine and Life ScienceAdverse drug reactions (ADRs) are closely associated with increased morbidity and mortality rates, prolonged hospitalization durations, and higher healthcare costs.
Jaechun Lee, Daehong Cho, Cheol-Woo Kim
doaj +1 more source
Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998–2005 [PDF]
, 2007 BACKGROUND: Adverse drug reactions (ADRs) are a frequent cause of mortality and morbidity to patients worldwide, with great associated costs to the healthcare providers including the NHS in England.
Bell, Derek +6 more
core +3 more sources
Use of psychoactive substances in students at a public university
ABCS Health Sciences, 2014 Introduction: The use of psychoactive substances by the student population has been the object of various studies in Brazil. Objective: To determine the prevalence of substance use among students.
Meire Luci da Silva +3 more
doaj +1 more source
Revista de Ciências Farmacêuticas Básica e Aplicada, 2021 Objective: To summarize evidence regarding the toxic potential of administering parabenscontaining cosmetics in humans. Methods: The systematic review followed the methodology proposed in Preferred Reporting Items for Systematic Reviews and Meta ...
Daiane de Freitas Resende +4 more
doaj
A randomized comparison between lercanidipine and amlodipine for efficacy and tolerability in patients with essential hypertension [PDF]
, 2016 Background: Lercanidipine, a newly added dihydropyridine, was compared with one of its older and time tested congener- amlodipine for their efficacy and tolerability.Methods: This was a prospective, double blind, parallel group study.
Choure, Balwant Kisanrao +3 more
core +3 more sources
Cutaneous adverse drug reactions in patients with peripheral blood eosinophilia during antituberculosis treatment [PDF]
The Korean Journal of Internal Medicine, 2019 Background/Aims Peripheral eosinophilia during tuberculosis (TB) treatment is common, but has not been fully evaluated. The aim of this study was to determine the prevalence and clinical significance of peripheral blood eosinophilia in patients ...
Tae-Ok Kim +5 more
doaj +1 more source
GraphSAW: A web-based system for graphical analysis of drug interactions and side effects using pharmaceutical and molecular data [PDF]
, 2015 Shoshi A, Hoppe T, Kormeier B, Ogultarhan V, Hofestädt R. GraphSAW: A web-based system for graphical analysis of drug interactions and side effects using pharmaceutical and molecular data. BMC Medical Informatics and Decision Making.
Hofestädt, Ralf +4 more
core +2 more sources
A comparison between two recommendations to conduct and report systematic reviews on drug’s safety
Systematic Reviews, 2019 Background Several recommendations are available to conduct and report a systematic review of adverse drug reactions. This study is aimed at identifying and comparing the methodologies of the two most commonly used recommendations to conduct and report ...
Ana Penedones +2 more
doaj +1 more source