Results 41 to 50 of about 314,543 (258)
Revista de Saúde Pública, 2022 OBJECTIVE To describe the frequency and characteristics of hospitalizations for/with adverse drug events in the Brazilian unified health system routine data.
Lunara Teles Silva +4 more
doaj +1 more source
Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults [PDF]
, 2009 This article describes the pharmacology of the novel atypical antidepressant drug agomelatine, critically reviews and evaluates its clinical use for the treatment of major depression, and suggests areas for further research.
Howland, RH
core +1 more source
Falls and Drugs in the Older Population: medical and societal consequences [PDF]
, 2011 Falls represent a major public health problem among older persons in western countries, since approximately a third of all persons aged 65 years and older experience at least one fall per year.
Hartholt, K.A. (Klaas)
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura +5 more
wiley +1 more source
Side effects of chronic systemic glucocorticoid therapy: what dermatologists should know [PDF]
Anais Brasileiros de DermatologiaIn dermatologists' clinical practice, the use of systemic glucocorticoids is recurrent for the management of different comorbidities that require chronic immunosuppression. The prescription of this medication requires caution and basic clinical knowledge
Lucas Campos Prudente Tavares +2 more
doaj +1 more source
Physicians' Experiences as Patients with Statin Side Effects: A Case Series. [PDF]
, 2017 Physicians are among those prescribed statins and therefore, subject to potential statin adverse effects (AEs). There is little information on the impact of statin AEs on physicians affected by them. We sought to assess the character and impact of statin
Golomb, Beatrice Alexandra +2 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Prevalência e características dos eventos adversos a medicamentos no Brasil
Cadernos de Saúde Pública, 2018 Resumo: O presente trabalho tem como objetivo descrever a prevalência e fatores associados a eventos adversos a medicamentos (EAM) referidos por usuários de medicamentos no Brasil.
Livia Alves Oliveira de Sousa +11 more
doaj +1 more source
"Farmacogenetica quale strumento della farmacovigilanza per la predittività delle reazioni avverse da farmaci" [PDF]
, 2011 Senza dubbio le reazioni avverse da farmaci rappresentano un problema clinico rilevante, circa il 6,5% dei ricoveri ospedalieri è correlato con una reazione avversa.
BARNINI, BARBARA
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source