Results 61 to 70 of about 310,100 (285)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Case report: leg ulcers resolving after discontinuation of clozapine for schizophrenia.

Psicosomática y Psiquiatría, 2021
There is a high prevalence of skin conditions and metabolic disturbances in patients with schizophrenia. Skin ulcers, in particular those of the lower extremities, mostly arise from arterial and/or venous pathology.
C Fragoeiro, C Machado, P Moura Ferreira
doaj   +1 more source

Assessing Pharmacokinetic Correlates of Escitalopram-Related Adverse Drug Reactions

Therapeutic Drug Monitoring
Supplemental Digital Content is Available in the Text. Background: To assess the pharmacokinetic correlates of reported adverse drug reactions (ADRs) under antidepressant treatment with escitalopram (ESC) using a large therapeutic drug monitoring ...
M. Kuzin, E. Haen, N. Kuzo, Katharina Endres, C. Hiemke, M. Paulzen, Georgios Schoretsanitis   +6 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Side Effects

Definitions, 2020
Side effects are ubiquitous in medicine and they often play a role in treatment de - cisions for patients and clinicians alike. Philosophers and health researchers often use side effects to illustrate issues with contemporary medical research and prac ...
Else Donder
semanticscholar   +1 more source

"Farmacogenetica quale strumento della farmacovigilanza per la predittività delle reazioni avverse da farmaci" [PDF]

, 2011
Senza dubbio le reazioni avverse da farmaci rappresentano un problema clinico rilevante, circa il 6,5% dei ricoveri ospedalieri è correlato con una reazione avversa.
BARNINI, BARBARA
core  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Prevalência e características dos eventos adversos a medicamentos no Brasil

Cadernos de Saúde Pública, 2018
Resumo: O presente trabalho tem como objetivo descrever a prevalência e fatores associados a eventos adversos a medicamentos (EAM) referidos por usuários de medicamentos no Brasil.
Livia Alves Oliveira de Sousa, Marta Maria de França Fonteles, Mirian Parente Monteiro, Sotero Serrate Mengue, Andréa Dâmaso Bertoldi, Tatiane da Silva Dal Pizzol, Noemia Urruth Leão Tavares, Maria Auxiliadora Oliveira, Vera Lucia Luiza, Luiz Roberto Ramos, Mareni Rocha Farias, Paulo Sergio Dourado Arrais   +11 more
doaj   +1 more source

Uncommon progression of toxoplasmic papillitis: patient perception and case report

Revista Brasileira de Oftalmologia, 2021
Ocular toxoplasmosis frequently presents as necrotizing retinochoroiditis and, less often, as peripapillary chorioretinitis and/or papillitis. The progression from papillitis to peripapillary retinochoroiditis has been rarely described.
Elcio Luiz Bonamigo, Eglas Emanuel Rossi, Maria do Carmo Nunes da Rosa, Ricardo Alexandre Stock, Rodrigo Rosa Sampaio, Ronei Carlos Lora   +5 more
doaj   +1 more source

What is the impact of antidepressant side effects on medication adherence among adult patients diagnosed with depressive disorder: A systematic review

Journal of Psychopharmacology
Background: Medication adherence is a prerequisite to achieving beneficial treatment outcomes. In major depressive disorder, many patients fail to complete medication regimens, raising concern for poor treatment outcomes.
Eleni Niarchou, LH Roberts, B. Naughton
semanticscholar   +1 more source