Results 231 to 240 of about 1,287,782 (264)
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2010
This chapter provides an overview of our current understanding of the mechanisms associated with the development of antimicrobial drug resistance, international differences in definitions of resistance, ongoing efforts to track shifts in drug susceptibility, and factors that can influence the selection of therapeutic intervention. The latter presents a
Marilyn, Martinez, Peter, Silley
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This chapter provides an overview of our current understanding of the mechanisms associated with the development of antimicrobial drug resistance, international differences in definitions of resistance, ongoing efforts to track shifts in drug susceptibility, and factors that can influence the selection of therapeutic intervention. The latter presents a
Marilyn, Martinez, Peter, Silley
openaire +2 more sources
Molecular Genetics, Microbiology and Virology (Russian)
Genetic control of different pathways of drug-resistance formation in bacteria is presented. Possible molecular mechanisms of “new” genes integration into the genomes by horizontal gene transfer are discussed. This review may be valuable for physicians, veterinarians and scientific researches engaged in bacterial evolution.
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Genetic control of different pathways of drug-resistance formation in bacteria is presented. Possible molecular mechanisms of “new” genes integration into the genomes by horizontal gene transfer are discussed. This review may be valuable for physicians, veterinarians and scientific researches engaged in bacterial evolution.
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Current Opinion in Pulmonary Medicine, 2000
There is increasing concern in many countries about the problem of drug-resistant tuberculosis, particularly so because no new classes of drugs have been developed for the treatment of tuberculosis since the 1960s. Although drug resistance is thought to be fairly common in some countries and rare in others, the global extent of this condition is not ...
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There is increasing concern in many countries about the problem of drug-resistant tuberculosis, particularly so because no new classes of drugs have been developed for the treatment of tuberculosis since the 1960s. Although drug resistance is thought to be fairly common in some countries and rare in others, the global extent of this condition is not ...
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Trends in Microbiology, 1994
The mechanisms of action of antiviral drugs and of drug resistance are known in remarkable detail, partly because X-ray crystallographic structures are known for many target viral proteins. Resistance usually involves amino acid substitutions in the target protein that prevent drug binding or prevent an enzyme from accepting the drug as a substrate ...
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The mechanisms of action of antiviral drugs and of drug resistance are known in remarkable detail, partly because X-ray crystallographic structures are known for many target viral proteins. Resistance usually involves amino acid substitutions in the target protein that prevent drug binding or prevent an enzyme from accepting the drug as a substrate ...
openaire +2 more sources
1994
Drug resistance is an ever present, dark shadow of cancer chemotherapy. Resistance developing as a consequence of treatment with cancer chemotherapeutic agents was a phenomenon recognized at the outset. In the days when the genome was generally considered to be static or fixed, tumor-cell drug resistance occurring in the patient, in animal models, and ...
J L, Biedler, B A, Spengler
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Drug resistance is an ever present, dark shadow of cancer chemotherapy. Resistance developing as a consequence of treatment with cancer chemotherapeutic agents was a phenomenon recognized at the outset. In the days when the genome was generally considered to be static or fixed, tumor-cell drug resistance occurring in the patient, in animal models, and ...
J L, Biedler, B A, Spengler
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Endeavour, 1984
Abstract Since it was introduced into Europe from South America by the Jesuits at the beginning of the 17th century, quinine has been one of the most effective drugs for the treatment of malaria. During this century a number of synthetic antimalarial drugs have been introduced but while these have had considerable success their extensive and ...
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Abstract Since it was introduced into Europe from South America by the Jesuits at the beginning of the 17th century, quinine has been one of the most effective drugs for the treatment of malaria. During this century a number of synthetic antimalarial drugs have been introduced but while these have had considerable success their extensive and ...
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Avoiding Drug Resistance in HIV Reverse Transcriptase
Chemical Reviews, 2021Maria E Cilento +2 more
exaly
Drug resistance in schistosomiasis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986Coles, GC +5 more
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Challenges and Opportunities in Cancer Drug Resistance
Chemical Reviews, 2021Richard A Ward +2 more
exaly