Results 121 to 130 of about 2,582,050 (300)

Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing. [PDF]

, 2013
BACKGROUND: The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus of this work was to characterize
Grace P McCormack, Crampin, Amelia C., Bansode, Vijay, McCormack, Grace P., Glynn, Judith R., Neil French, Ram K Shrestha, Travers, Simon A, Simon A Travers, French, Neil, Glynn, Judith R, Crampin, Amelia C, Vijay Bansode, Judith R Glynn, Vijay Bansode, Amelia C Crampin, McCormack, Grace P, Travers, Simon A., Shrestha, Ram K., Ngwira, Bagrey, Shrestha, Ram K, Bagrey Ngwira, Bansode Vijay, French Neil, Ngwira Bagrey, Crampin Amelia C, McCormack Grace P, Travers Simon A, Glynn Judith R, Shrestha Ram K   +29 more
core   +2 more sources

The hidden burden of sleep in adolescents with idiopathic generalized epilepsy

Epileptic Disorders, EarlyView.
Abstract Background Idiopathic Generalized Epilepsies (IGEs) are electroclinical syndromes characterized by distinct seizure types, EEG patterns, and presumed polygenic inheritance. While seizure prognosis is often favorable, sleep disturbances, behavioral and emotional difficulties, and executive function impairment are common, especially during ...
Carlo Alberto Quaranta, Martina Paola Zanaboni, Elena Ripamonti, Gaia Garghetti, Massimiliano Celario, Serena Grumi, Helene Vitali, Valentina De Giorgis, Ludovica Pasca   +8 more
wiley   +1 more source

Serum α-Synuclein in Pediatric Refractory Epilepsy: Correlation with Diagnosis and Clinical Severity

Medicina
Background and Objectives: Epilepsy is a common neurological disrupt that involves recurring seizures. α-Synuclein (α-Syn), one of the most abundant proteins in the nervous system, is implicated in both neurodegenerative conditions and epilepsy.
Aida M. S. Salem, Dalia Saber Morgan, Marwa O. Elgendy, Mohamed E. A. Abdelrahim, Noura Mostafa Mohamed Mostafa, Asmaa Saleh, Manar M. Abdel-Aziz, Asmaa K. Ramadan   +7 more
doaj   +1 more source

Management of epilepsy [PDF]

, 1989
Figures for the incidence of epilepsy in Malta are not available. The overall figure for epilepsy given by the Royal College of General Practitioners (Reid 1960) is 4.82 per 1,000 population.
Galea Debono, Anthony
core  

Preoperative limbic cortical thinning in mesial temporal lobe epilepsy surgical candidates is associated with pre‐existing and de novo postoperative depression

Epileptic Disorders, EarlyView.
Abstract Objective Depression is common in mesial temporal lobe epilepsy (mTLE), but its neuroanatomical basis—and overlap with major depressive disorder (MDD)—remains poorly defined. We investigated whether the cortical and subcortical alterations reported in MDD are also present in mTLE and leveraged the frequent occurrence of depression after ...
Philip Fink‐Jensen, Brice Ozenne, Ane Kloster, Bo Jespersen, Kirsten Vinter, Guido Rubboli, Martin Balslev Jørgensen, Sandor Beniczky, Melanie Ganz, Lars Hageman Pinborg   +9 more
wiley   +1 more source

Drug-resistant epilepsy treated with a vagus nerve stimulator – case report and literature review

Journal of Education, Health and Sport
The average incidence of epilepsy worldwide is estimated at 7.60 cases per 1,000 inhabitants, with an average annual incidence of 67.77 cases per 100,000 inhabitants. Epilepsy is one of the most common neurological diseases. However, it is not a disease
Michał Leśniewski, Dominika Brzuchacz, Patrycja Błaszczeć, Agata Miecznikowska, Natalia Siwak, Iwona Welian-Polus, Klaudia Szukała, Magdalena Chrościńska-Krawczyk   +7 more
doaj   +1 more source

Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese

, 2007
There is accumulating evidence to suggest that overexpression of efflux drug transporters at the blood-brain barrier, by reducing antiepileptic drug (AED) accumulation in the seizure foci, contributes to drug resistance in epilepsy.
Hui, ACF, Wong, V, Baum, L, Lui, CH, Sin, NC, Yu, E, Ng, PW, Kwan, P, Wong, LKS   +8 more
core   +1 more source

Exploring the efficacy and safety of perampanel in epilepsia partialis continua: A case series

Epileptic Disorders, EarlyView.
Abstract Background Epilepsia partialis continua (EPC) is a form of focal motor status epilepticus (SE), which is commonly drug‐resistant requiring treatment with multiple antiseizure medications (ASM). There are no established guidelines for pharmacological management.
Setareh Lahsaee, Kristin M. Ikeda, Stephanie Woodroffe, Benjamin P. Whatley   +3 more
wiley   +1 more source

Beyond the seizures: Ketogenic Diets in the battle against drug-resistant epilepsy

Journal of Education, Health and Sport
Introduction: Epilepsy is a chronic, non-infectious and one of the most common neurological disease. About 70 million people worldwide suffer from it and these are patients of all ages. Despite the existence of many anticonvulsants and multiple lines of
Natalia Domańska, Małgorzata Bojarska, Julia Bogucka, Anna Brzyska, Michalina Kosowska, Halina Piecewicz-Szczęsna   +5 more
doaj   +1 more source

Facilitating the timely diagnosis of Lennox–Gastaut syndrome: A checklist to support clinical practice

Epileptic Disorders, EarlyView.
Abstract Objective To develop and evaluate a simple‐to‐use checklist to support physicians with the timely diagnosis of Lennox–Gastaut syndrome (LGS). Methods A panel of 10 pediatric and adult epileptologists used the International League Against Epilepsy (ILAE) criteria for LGS classification and definition to develop seven questions for the checklist,
Nicola Specchio, Alexis Arzimanoglou, Stéphane Auvin, Antonio Gil‐Nagel, Lieven Lagae, Rima Nabbout, Susanne Schubert‐Bast, Adam Strzelczyk, Eugen Trinka, J. Helen Cross   +9 more
wiley   +1 more source